Inquiry into Life
16th Edition
ISBN: 9781260482638
Author: Mader, Sylvia
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 23.1, Problem 4LO
Predict outcome ratios and probabilities for problems based on Mendelian patterns of inheritance.
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Chapter 23 Solutions
Inquiry into Life
Ch. 23.1 - Describe how Mendel's law of segregation and law...Ch. 23.1 - Define the term allele, and explain what it means...Ch. 23.1 - Contrast genotype and phenotype, and use...Ch. 23.1 - Predict outcome ratios and probabilities for...Ch. 23.1 - Prob. 1QTCCh. 23.1 - 2. Decide the reasons listed in the feature, what...Ch. 23.1 - Prob. 3QTCCh. 23.1 - Distinguish between the terms genotype and...Ch. 23.1 - Explain the purpose of testcross.Ch. 23.1 - Prob. 3CYP
Ch. 23.1 - Describe the types of process that result in a 3:1...Ch. 23.2 - Recognize autosomal dominant and autosomal...Ch. 23.2 - Analyze pedigree to determine the probability of a...Ch. 23.2 - Describe the characteristics of a Pedigree for an...Ch. 23.2 - Prob. 2CYPCh. 23.3 - Prob. 1LOCh. 23.3 - Prob. 2LOCh. 23.3 - Describe polygenic inheritance.Ch. 23.3 - What would be the potential consequences if one of...Ch. 23.3 - Prob. 2QTCCh. 23.3 - Prob. 1CYPCh. 23.3 - Prob. 2CYPCh. 23.4 - Prob. 1LOCh. 23.4 - Understand how scientists determine the effect of...Ch. 23.4 - Prob. 1CYPCh. 23.4 - Prob. 2CYPCh. 23 - Prob. C2BYBCh. 23 - Prob. S5.4BYBCh. 23 - Prob. S5.6BYBCh. 23 - The law of segregation states all of the following...Ch. 23 - Prob. 2ACh. 23 - Prob. 3ACh. 23 - Prob. 4ACh. 23 - Prob. 5ACh. 23 - Prob. 6ACh. 23 - Which of the following does not have an autosomal...Ch. 23 - 8. Which of the following does not describe the...Ch. 23 - Prob. 9ACh. 23 - Prob. 10ACh. 23 - Prob. 11ACh. 23 - Prob. 12ACh. 23 - Prob. 1TCCh. 23 - How would you determine whether a disease in...Ch. 23 - Prob. 3TC
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- Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. If Sarah carries the mutant cancer allele and Adam carries the mutant heart disease allele, what is the chance that they would have a child who is free of both diseases? Are these good odds?arrow_forwardPedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. Would you want to know the results of the cancer, heart disease, and TSD tests if you were Sarah and Adam? Is it their responsibility as potential parents to gather this type of information before they decide to have a child?arrow_forwardidentify Mendelian inheritance patterns and pedigree analysis.arrow_forward
- You have used the Chi-Square Goodness of Fit test quite extensively. How useful do you find it in terms of it's ability to determine different modes of inheritance from observed data? Please provide a few pros and/or cons, and please be specific. Typed pleasearrow_forwardDescribe two examples that show deviation or extensions of simple Mendelian genetics.arrow_forwardCompare and contrast non-mendelian inheritance in human traitsarrow_forward
- What can you conclude based on the value of the computed Chi-square? How can you relate the two principles of Mendel to Chi-Square Values?arrow_forwardGregor Mendel’s basic principles of inheritance say that each trait is controlled by just one gene with just two alleles, and that each allele is clearly dominant or recessive to the other. However, we now know that many (if not most) traits are not actually inherited according to these rules. Name and describe two other (i.e., non-Mendelian) inheritance patterns, including how each one works, and a give specific example of an actual trait that follows each pattern.arrow_forwardin own understanding, what is mendelian genetics?arrow_forward
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