Organic Chemistry (8th Edition)
Organic Chemistry (8th Edition)
8th Edition
ISBN: 9780134042282
Author: Paula Yurkanis Bruice
Publisher: PEARSON
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Chapter 23.6, Problem 20P
Interpretation Introduction

Interpretation:

The enzyme catalysed reaction and the names of the required coenzymes should be determined.

Concept introduction:

In an enzyme catalysed reaction that requires coenzymesB12, a group bonded to one carbon changes places with a hydrogen bonded to an adjacent carbanion.

Biotin (vitamin H) is the coenzyme required by enzymes that catalyse the carboxylation of a carbon adjacent to carbonyl group.

CoenzymesB12: The coenzyme required by enzymes catalyses certain rearrangement reactions.

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①   H+ +  HCO3─ +  Pi   →  Carboxyphosphate  + H2O               ∆G0’ =+19.7 kJ mol-1 ②       ATP  +  H2O   →     ADP  +  Pi  +  H+                                  ∆G0’ = ─30.5 kJ mol-1 ③ Carboxyphosphate + pyruvate  →   oxaloacetate + Pi                 ∆G0’ = ??? kJ mol-1                       ④  Overall reaction: ATP + HCO3─ +  pyruvate   →   oxaloacetate + ADP + Pi                ∆G0’ = ─2.1 kJ mol-1  a) Use reactions ①, ② and overall reaction ④ to calculate the ∆G0’ for the formation of oxaloacetate from pyruvate and carboxyphosphate (reaction ③ above). Use reactions ①, ② and overall reaction ④ to calculate the ∆G0’ for the formation of oxaloacetate from pyruvate and carboxyphosphate (reaction ③ above). b) Now calculate ∆G0’ for the formation of oxaloacetate from pyruvate and bicarbonate in the absence of ATP.  c) Explain the difference in your answers to parts a and b.
(i) Deficiency of which vitamin causes rickets?(ii) Give an example for each of fibrous protein and globular protein.(iii) Write the product formed on reaction of D-glucose with Br2 water.
Report Table CHO.15: Hydrolysis Conclusions for Starch     Iodine test observation Conclusion for Iodine test Benedict's test observation Conclusion for Benedict's test Starch + H2O(negative control) Blue to black solution   Choose... A. Amylose presnet  B. Amylose not present    Blue solution   Choose... A. Reducing sugars not presnet  B. Reducing sugars presnet     Starch + HCl(potential hydrolysis) more blue-black compared to starch+water   Choose...   A. More amylose presnet B. Less amylose presnet C. No change  no longer blue compared to starch+water   Choose... A. More reducing sugar present B. Less reducing sugar present C. No change    Did hydrolysis of starch occur in the presence of acid?   A. yes  B. no Give a summary of your results for the hydrolysis of disaccharides and polysaccharides. In your own words, explain why you saw these results.

Chapter 23 Solutions

Organic Chemistry (8th Edition)

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