Chapter 24, Problem 11P

Glaucoma is the second leading cause of vision loss worldwide. High intraocular pressure (pressure inside the eye) almost always accompanies vision loss. It is postulated that the high pressure damages a subset of cells in the eye that are responsible for vision. One investigator theorizes that the relationship betweenvision loss and pressure can be described as

$VL=A\text{ exp }\left(k{\int }_{25}^t\left(p-13\right)dt\right)$

whereVL is percent vision loss, P is intraocular pressure (mm Hg), t is time (years), and k and A are constants. Using the data below from three patients, estimate the constants k and A.