Concept explainers
Interpretation: A stepwise mechanism for the conversion of
Concept Introduction: Aldol reaction is the condensation reaction of the
The aldol reaction that takes place within the same molecule in the presence of strong base is known as intramolecular aldol reactions. This reaction generally takes place within the dicarbonyl compounds in which one carbonyl group forms the enolate ion that acts as a nucleophile and the carbonyl carbon of the second carbonyl group acts as an electrophile.
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ORGANIC CHEMISTRY-MOLYMOD PACKAGE
- 2-Pentylcinnamaldehyde, commonly called osal, is a perfume ingredient with a jasmine-like odor. Flosal is an α,βunsaturated aldehyde made by a crossed aldol reaction between benzaldehyde (C6H5CHO) and heptanal (CH3CH2CH2CH2CH2CH2CHO), followed by dehydration. Draw a stepwise mechanism for the following reaction that prepares osal.arrow_forwardPlease draw reaction out of: prop-1-yne reacts with H2 and palladium on carbon butan-2-one reacts with sodium borohydride/H+ Propanoyl bromide reacts with methanol butan-2-one reacts with methylmagnesium bromide in a Grignard reactionarrow_forwardDraw the products formed when A or B is treated with each reagent. In some cases, no reaction occurs.a. NaBH4, CH3OHb. [1] LiAlH4; [2] H2Oc. [1] CH3MgBr (excess); [2] H2Od. [1] C6H5Li (excess); [2] H2Oe. Na2Cr2O7, H2SO4, H2Oarrow_forward
- Draw the substitution product formed (including stereochemistry) when (R)-hexan-2-ol is treated with each series of reagents: (a) NaH, followed by CH3I; (b) TsCl and pyridine, followed by NaOCH3; (c) PBr3, followed by NaOCH3. Which two routes produce identical products?arrow_forward2-Pentylcinnamaldehyde, commonly called flosal, is a perfume ingredient with a jasmine-like odor. Flosal is an α,β-unsaturated aldehyde made by a crossed aldol reaction between benzaldehyde (C6H5CHO) and heptanal (CH3CH2CH2CH2CH2CH2CHO), followed by dehydration. Draw a stepwise mechanism for the following reaction that prepares flosal.arrow_forwardDraw the major elimination product for the reaction of 2-bromo2-methylbutane with A) KOH B) KOtBu C) 1-butanol D) 1-propanolarrow_forward
- Epoxides are converted to allylic alcohols with nonnucleophilic bases such as lithium diethylamide [LiN(CH2CH3)2]. Draw a stepwise mechanism for the conversion of 1,2-epoxycyclohexane to cyclohex-2en-1-ol with this base. Explain why a strong bulky base must be used in this reaction.arrow_forwardWhat product is formed by ring-closing metathesis of each compound?arrow_forward2-Pentylcinnamaldehyde, commonly called flosal, is a perfume ingredient with a jasminelike odor. Flosal is an α,β-unsaturated aldehyde made by a crossed aldol reactionbetween benzaldehyde (C6H5CHO) and heptanal (CH3CH2CH2CH2CH2CH2CHO), followed by dehydration. Draw a stepwise mechanism for the following reaction that prepares flosal.arrow_forward
- Design a stepwise synthesis to convert cyclopentanone and 4-bromobutanal to hydroxyl aldehyde A.arrow_forwardproduct obtained when pent-1-yne is treated with dil.H2SO4 in presence of HgSO4arrow_forwardDesign a stepwise synthesis to convert cyclopentanone and 4-bromobutanal to hydroxy aldehyde A.arrow_forward