Interpretation: The bicyclic ring systems among the given systems that can be prepared by an intermolecular Robinson annulation are to be stated.
Concept Introduction: The combination of the Michael reaction and intramolecular aldol reaction in which the formation of a ring takes place is known as Robinson annulation reaction. In this reaction, the carbonyl compound is treated with a base which leads to the elimination of a proton from the
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ORGANIC CHEMISTRY-MOLYMOD PACKAGE
- Which of the following is most susceptible towards nucleophilic aromatic substitution?arrow_forwarddetermine which is the Hoffman elimination product from the two and provide the mechanism belowarrow_forwardIdentify the product of the following reaction. (Hint: It has a fused bicyclic ring.)arrow_forward
- When a single compound contains both a nucleophile and a leaving group, an intramolecular reaction occurs. With this in mind, what is the structure and stereochemistry of the following reaction?arrow_forwardDraw a detailed mechanism for the FeBr3@catalyzed reaction of ethylbenzene with bromine, and show why the sigma complex (and the transition state leading to it) is lower in energy for substitution at the ortho and para positions than it is for substitution at the meta position.arrow_forwardName the kind of sigmatropic rearrangement that occurs in the following reaction.arrow_forward
- Which of the following within a tetrahedral intermediate leaves most readily as a nucleofuge? * a-OH b-OCH2CH3 c-OCOCH3 d-NH2arrow_forwardShow the structures for the major/significant organic product(s) expected for the following eleven reactions or sequences of reactions. If there is a major and minor productcircle the major product. Show all relevant stereochemistry.arrow_forwardProvide the missing reagent(s) needed to complete the following reactions. For each reaction determine whether the mechanism went through a carbocation, a 3-membered ring intermediate, or was concerted. Also indicate whether the reaction follows Markovnikov’s Rule, and is syn or anti addition.arrow_forward
- Draw the structures of A - D from the following electrocyclic and cycloaddition reactions.arrow_forwardWhat reaction presented in this chapter is occurring in the following equation? Explain the resulting stereochemistry of the reaction.arrow_forwardgive the major product of the following reactions with the appropriate stereochemistry and regiochemistry.arrow_forward
- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning