Chapter 24, Problem 24.49P

Interpretation Introduction

(a)

Interpretation: The product (including stereochemistry) that is formed in the given intramolecular reaction is to be predicted.

Concept introduction: In crossed claisen condensation reaction, the base abstracts the acidic proton from $\text{α}-$ carbon atom of an ester to form enolate. This enolate reacts with carbonyl group of other ester that leads to the formation of a $\text{β-keto}\text{ester}$. The crossed Claisen condensation always takes place between the two different carbonyl compounds.

Interpretation Introduction

(b)

Interpretation: The product (including stereochemistry) that is formed in the given intramolecular reaction is to be predicted.

Concept introduction: The replacement or substitution of one functional group with another different functional group in any chemical reaction is termed as substitution reaction. The nucleophilic reaction that consists of bimolecular as well as bond-making and bond-breaking steps is termed as ${\text{S}}_{\text{N}}\text{2}$ reactions. This is a one-step reaction in which both nucleophile and substrate participate in the rate determining step.