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Concept explainers
Interpretation:
It should be determined that how many rounds of the lipogenesis cycle are needed to synthesize stearic acid,
Concept introduction:
Fatty acids are aliphatic mono-
Lipogenesis is the
Lipogenesis requires;
Synthesis of fatty acids and glycerol
Activation of fatty acids by CoA and glycerol by glycerokinase
The combination of activated fatty acids and activated glycerol to produce TAG (triacylglycerol)
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Chapter 24 Solutions
EBK FUNDAMENTALS OF GENERAL, ORGANIC, A
- Suggest the effects of each of the following mutations on the physiologicalrole of chymotrypsinogen:(a) R15S(b) C1S(c) T147Sarrow_forwardWhy are the protein-digesting enzymes trypsin and chymotrypsin secreted as the zymogen chymotrypsinogen?arrow_forwardOn the right is a diagram of plasma concentration of three metabolites: glucose, B- hydroxybutyrate, and free fatty acid of an experimental animal over weeks of starvation. 4. (a) Label the lines with the names of the three metabolites. Yellow: Red: 10 20 30 40 Blue: Days of starvation (b) What factor in the plasma binds to and transports free fatty acid (c) Where was B-hydroxybutyrate produced? Why it is produced? What are the purposes of producing it (d) How B-hydroxybutyrate is used as fuel in extrahepatic cells? Write down the reactions, enzymes, and cofactors (No need to elaborate on the TCA cycle). (e) How many ATP molecules or equivalent are generated after complete oxidation of one molecule of B-hydroxybutyrate? Show your calculations. Hint: You need to consider ATP consumption for bypassed steps that may normally yield or consume AT Plasma concentration (mM)arrow_forward
- What does the fact that the two histograms overlap as much asthey do indicate about the extent to which PCSK9 determinesplasma LDL cholesterol levels?arrow_forwardAs less glucose is available due to a low carb diet what happens to the ability of the TCA cycle to proceed?arrow_forwardHyaluronidase hydrolyzes hyaluronic acid into monosaccharides to facilitate diffusion of bacteria into tissues?arrow_forward
- What do the peaks of C6H12O2 show?arrow_forwardVitamin K questionsa) What transformation of glutamate side chains is Vitamin K (as its reduced form, VitaminKH2) involved in, and what is the relevance of this reaction to blood clotting?b) How does the blood thinner Coumadin (warfarin) prevent clotting?c) How can the dietary intake of large amounts of green vegetables, such as broccoli or kaleinterfere with the action of Coumadin?arrow_forwardWhat is the origin of the triacylglycerols transported by very low-density lipoproteins?arrow_forward