CAMPBELL BIOLOGY IN FOCUS-W/MASTR.BIO.
3rd Edition
ISBN: 9780134875040
Author: Urry
Publisher: PEARSON
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Chapter 24.3, Problem 4CC
WHAT IF? If a nonpathogenic bacterium were to acquire resistance to antibiotics, could this strain pose a health risk to people? In general, how does DNA transfer among bacteria affect the spread of resistance genes?
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"On the rapidity of antibiotic resistance evolution facilitated by a concentration gradient"
ABSTRACT
The rapid emergence of bacterial strains resistant to multiple antibiotics is posing a growing public health risk. The mechanisms underlying the rapid evolution of drug resistance are, however, poorly understood. The heterogeneity of the environments in which bacteria encounter antibiotic drugs could play an important role. E.g., in the highly compartmentalized human body, drug levels can vary substantially between different organs and tissues. It has been proposed that this could facilitate the selection of resistance mutants, and recent experiments support this. To study the role of spatial heterogeneity in the evolution of drug resistance, we present a quantitative model describing an environment subdivided into relatively isolated compartments with various antibiotic concentrations, in which bacteria evolve under the stochastic processes of proliferation, migration, mutation and…
In generalized transduction....
Choose from the answers below:
random fragments of degraded bacterial DNA are packaged in phage particles.
the maximum size of transduced DNA fragments is dependent on the size of the phage particles.
the transducing DNA fragments are generated by faulty excision of a prophage from the host genome.
a and b, but not c
b and c, but not a
Chapter 24 Solutions
CAMPBELL BIOLOGY IN FOCUS-W/MASTR.BIO.
Ch. 24.1 - What hypothesis did Miller test in his classic...Ch. 24.1 - How would the appearance of protocells have...Ch. 24.1 - Prob. 3CCCh. 24.1 - Prob. 4CCCh. 24.2 - Contrast the cellular and DNA structures of...Ch. 24.2 - Distinguish between the four major modes of...Ch. 24.2 - Prob. 3CCCh. 24.2 - Prob. 4CCCh. 24.3 - Although rare on a per gene basis, new mutations...Ch. 24.3 - Distinguish between the three mechanisms by which...
Ch. 24.3 - In a rapidly changing environment, which bacterial...Ch. 24.3 - WHAT IF? If a nonpathogenic bacterium were to...Ch. 24.4 - Explain how molecular systematics and metagenomics...Ch. 24.4 - WHAT IF? What would the discovery of a bacterial...Ch. 24.5 - Explain how prokaryotes, though small, can be...Ch. 24.5 - Prob. 2CCCh. 24.5 - Prob. 3CCCh. 24.5 - Prob. 4CCCh. 24 - Which of the following steps has not yet been...Ch. 24 - Fossilized stromatolites A. more than 2.8 billion...Ch. 24 - Prob. 3TYUCh. 24 - Photoautotrophs use A. light as an energy source...Ch. 24 - Which of the following statements is not true? A....Ch. 24 - Prob. 6TYUCh. 24 - Prob. 7TYUCh. 24 - SCIENTIFIC INQUIRY INTERPRET THE DATA The...Ch. 24 - FOCUS ON EVOLUTION In patients infected with...Ch. 24 - FOCUS ON ENERGY AND MATTER In a short essay (about...Ch. 24 - Prob. 11TYU
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- "On the rapidity of antibiotic resistance evolution facilitated by a concentration gradient" ABSTRACT The rapid emergence of bacterial strains resistant to multiple antibiotics is posing a growing public health risk. The mechanisms underlying the rapid evolution of drug resistance are, however, poorly understood. The heterogeneity of the environments in which bacteria encounter antibiotic drugs could play an important role. E.g., in the highly compartmentalized human body, drug levels can vary substantially between different organs and tissues. It has been proposed that this could facilitate the selection of resistance mutants, and recent experiments support this. To study the role of spatial heterogeneity in the evolution of drug resistance, we present a quantitative model describing an environment subdivided into relatively isolated compartments with various antibiotic concentrations, in which bacteria evolve under the stochastic processes of proliferation, migration, mutation and…arrow_forwardDescribe the 3 ways in which bacteria can transfer genetic material to each other via horizontal gene transfer. Be sure to explain the following: How is DNA transferred between bacteria, is there direct contact between bacteria and whether a plasmid is involved or not.arrow_forwardIf graft qnd corruption are diseases, how do you propose to ameliorate their ravages? If they are only symptoms, what is the disease and how do you propose to treat it?arrow_forward
- Name 3 ways in which genetic information of bacteria can be changed?arrow_forwardOne of the reasons why phage therapy has not been applied widely is that bacteria can become resistant to bacteriophages as well, through mutations in genes encoding for specific proteins. What would be a protein in the bacterial cell that, if mutated, would make that cell resistant to phage infection?arrow_forwardResults from a Kirby Bauer antibiotic assay on a Gram-negative bacterial culture are described as follows: A) the bacterium is resistant to penicillin, an antibiotic that targets synthesis of the peptidoglycan cell wall and B) the bacterium is resistant to tetracycline, an antibiotic that targets the small subunit of the ribosome, inhibiting protein synthesis. Which of the results represents intrinsic resistant and which represents acquired resistants?arrow_forward
- Identify the most mistaken (wrong) choice: a) Transcription machinery and an enhancer can bind to the chromosome at the same time. b) Organic matters may interfere with heat treatment of bacterial growth control. ( c) Nitrocellulose can be used to filter out microorganisms from a liquid solution. d) Time to kill a bacterial culture is not proportional to the number of microbes in the culturearrow_forwardBriefly discuss the following questions in 3 to 5 sentences. What is horizontal gene transfer? What are the three mechanisms for this to occur in bacteria? What are the components needed for the processes of transformation, conjugation, and transduction? How does each process occur? What genes are involved in each process? How do generalized and specialized transduction differ? What is the end result of each? What is recombination? What is the importance to bacteria & archaea? What are the two types of recombination? What are the details of each type? What components are needed for each type?arrow_forwardWhat is wrongly matched? A) None of the above B) Transfer of genetic material from 1 cell to --- conjugation. Another involving cell to cell contact C) Transfer of DNA from 1 cell to another by a Bacteriophage---Transduction D) Bacterial cell in which the F factor has become integrated---HFrarrow_forward
- We have two specific strains of E. coli that have shown horizontal gene transfer (HGT) when mixed. To experimentally determine the method of HGT that is happening, the following conditions are set up in different tubes of culture media: A) Donor and recipient strain mixed together (control - no treatment). B) Donor and recipient strains mixed together, DNase added (can digest DNA in solution, not within cells).C) Special tube containing a membrane filter (with pores that allow DNA and viruses to pass through, but not bacterial cells) that separates two compartments. Donor strain is added on one side, the recipient strain on the other (they are separated by the filter).D) Donor and recipient strains mixed together, with chemical that inactivates viruses (chemical affects bacteriophages in solution so they are unable to attach to cells). The results: Tubes A, B, and D: HGT was observed. Tube C: HGT was NOT observed. Based on this, which type of HGT was occurring? Conjugation,…arrow_forward"On the rapidity of antibiotic resistance evolution facilitated by a concentration gradient" The rapid emergence of bacterial strains resistant to multiple antibiotics is posing a growing public health risk. The mechanisms underlying the rapid evolution of drug resistance are, however, poorly understood. The heterogeneity of the environments in which bacteria encounter antibiotic drugs could play an important role. E.g., in the highly compartmentalized human body, drug levels can vary substantially between different organs and tissues. It has been proposed that this could facilitate the selection of resistance mutants, and recent experiments support this. To study the role of spatial heterogeneity in the evolution of drug resistance, we present a quantitative model describing an environment subdivided into relatively isolated compartments with various antibiotic concentrations, in which bacteria evolve under the stochastic processes of proliferation, migration, mutation and death.…arrow_forward"On the rapidity of antibiotic resistance evolution facilitated by a concentration gradient" The rapid emergence of bacterial strains resistant to multiple antibiotics is posing a growing public health risk. The mechanisms underlying the rapid evolution of drug resistance are, however, poorly understood. The heterogeneity of the environments in which bacteria encounter antibiotic drugs could play an important role. E.g., in the highly compartmentalized human body, drug levels can vary substantially between different organs and tissues. It has been proposed that this could facilitate the selection of resistance mutants, and recent experiments support this. To study the role of spatial heterogeneity in the evolution of drug resistance, we present a quantitative model describing an environment subdivided into relatively isolated compartments with various antibiotic concentrations, in which bacteria evolve under the stochastic processes of proliferation, migration, mutation and death.…arrow_forward
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genetic recombination strategies of bacteria CONJUGATION, TRANSDUCTION AND TRANSFORMATION; Author: Scientist Cindy;https://www.youtube.com/watch?v=_Va8FZJEl9A;License: Standard youtube license