(a) Interpretation: The reason corresponding to the fact that phentermine cannot be made by reductive amination reaction is to be stated. Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

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Answer 1

Question

Chapter 25, Problem 25.16P

Interpretation Introduction

(a)

Interpretation: The reason corresponding to the fact that phentermine cannot be made by reductive amination reaction is to be stated.

Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

Interpretation Introduction

(b)

Interpretation: The systematic name for phentermine, is to be predicted.

Concept introduction: IUPAC nomenclature is a systematic way of naming the organic compounds. The basic principles of IUPAC naming for hydrocarbon are:

1. The hydrocarbon is named after the carbon chain containing higher number of carbon atoms.

2. The parent alkane containing amino group is named as alkane with suffix amine.

3. When the nitrogen atom of amine is substituted with alkyl groups, then the amine is named with prefix N before the alkyl groups.

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Students have asked these similar questions

What carboxylic acid and amine are needed to synthesize the pain reliever phenacetin? Phenacetin was once a component of the over-the-counter pain reliever APC (aspirin, phenacetin, caffeine), but it is no longer used because of its kidney toxicity.

(a) Explain why phentermine [PhCH2C(CH3)2NH2] can’t be made by a reductive amination reaction.(b) Give a systematic name for phentermine, one of the components of the banned diet drug fen–phen.

Fenfluramine and phentermine are two components of fen–phen, an appetite suppressant withdrawn from the market in 1997 after it was shown to damage the heart valves in some patients. What products are formed when fenfluramine and phentermine are each treated with acetic acid (CH3CO2H)?

Answer 2

Question

Chapter 25, Problem 25.16P

Interpretation Introduction

(a)

Interpretation: The reason corresponding to the fact that phentermine cannot be made by reductive amination reaction is to be stated.

Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

Interpretation Introduction

(b)

Interpretation: The systematic name for phentermine, is to be predicted.

Concept introduction: IUPAC nomenclature is a systematic way of naming the organic compounds. The basic principles of IUPAC naming for hydrocarbon are:

1. The hydrocarbon is named after the carbon chain containing higher number of carbon atoms.

2. The parent alkane containing amino group is named as alkane with suffix amine.

3. When the nitrogen atom of amine is substituted with alkyl groups, then the amine is named with prefix N before the alkyl groups.

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Answer 3

Question

Chapter 25, Problem 25.16P

Interpretation Introduction

(a)

Interpretation: The reason corresponding to the fact that phentermine cannot be made by reductive amination reaction is to be stated.

Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

Interpretation Introduction

(b)

Interpretation: The systematic name for phentermine, is to be predicted.

Concept introduction: IUPAC nomenclature is a systematic way of naming the organic compounds. The basic principles of IUPAC naming for hydrocarbon are:

1. The hydrocarbon is named after the carbon chain containing higher number of carbon atoms.

2. The parent alkane containing amino group is named as alkane with suffix amine.

3. When the nitrogen atom of amine is substituted with alkyl groups, then the amine is named with prefix N before the alkyl groups.

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Answer 4

Question

Chapter 25, Problem 25.16P

Interpretation Introduction

(a)

Interpretation: The reason corresponding to the fact that phentermine cannot be made by reductive amination reaction is to be stated.

Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

Interpretation Introduction

(b)

Interpretation: The systematic name for phentermine, is to be predicted.

Concept introduction: IUPAC nomenclature is a systematic way of naming the organic compounds. The basic principles of IUPAC naming for hydrocarbon are:

1. The hydrocarbon is named after the carbon chain containing higher number of carbon atoms.

2. The parent alkane containing amino group is named as alkane with suffix amine.

3. When the nitrogen atom of amine is substituted with alkyl groups, then the amine is named with prefix N before the alkyl groups.

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Answer 5

Chapter 25, Problem 25.16P

Interpretation Introduction

(a)

Interpretation: The reason corresponding to the fact that phentermine cannot be made by reductive amination reaction is to be stated.

Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

Interpretation Introduction

(b)

Interpretation: The systematic name for phentermine, is to be predicted.

Concept introduction: IUPAC nomenclature is a systematic way of naming the organic compounds. The basic principles of IUPAC naming for hydrocarbon are:

1. The hydrocarbon is named after the carbon chain containing higher number of carbon atoms.

2. The parent alkane containing amino group is named as alkane with suffix amine.

3. When the nitrogen atom of amine is substituted with alkyl groups, then the amine is named with prefix N before the alkyl groups.

Answer 6

Chapter 25, Problem 25.16P

Interpretation Introduction

(a)

Interpretation: The reason corresponding to the fact that phentermine cannot be made by reductive amination reaction is to be stated.

Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

Answer 7

Chapter 25, Problem 25.16P

Interpretation Introduction

(a)

Interpretation: The reason corresponding to the fact that phentermine cannot be made by reductive amination reaction is to be stated.

Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

Answer 8

Interpretation Introduction

(b)

Interpretation: The systematic name for phentermine, is to be predicted.

Concept introduction: IUPAC nomenclature is a systematic way of naming the organic compounds. The basic principles of IUPAC naming for hydrocarbon are:

1. The hydrocarbon is named after the carbon chain containing higher number of carbon atoms.

2. The parent alkane containing amino group is named as alkane with suffix amine.

3. When the nitrogen atom of amine is substituted with alkyl groups, then the amine is named with prefix N before the alkyl groups.

Answer 9

Interpretation Introduction

(b)

Interpretation: The systematic name for phentermine, is to be predicted.

Concept introduction: IUPAC nomenclature is a systematic way of naming the organic compounds. The basic principles of IUPAC naming for hydrocarbon are:

1. The hydrocarbon is named after the carbon chain containing higher number of carbon atoms.

2. The parent alkane containing amino group is named as alkane with suffix amine.

3. When the nitrogen atom of amine is substituted with alkyl groups, then the amine is named with prefix N before the alkyl groups.

Answer 10

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Answer 11

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Answer 12

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Answer 13

Ch. 25 - Prob. 25.1P Ch. 25 - Prob. 25.2P Ch. 25 - Prob. 25.3P Ch. 25 - Prob. 25.4P Ch. 25 - Prob. 25.5P Ch. 25 - Prob. 25.6P Ch. 25 - Problem 25.7 Draw the product of each...Ch. 25 - Prob. 25.8P Ch. 25 - Prob. 25.9P Ch. 25 - Prob. 25.10P

Solution Summary: The author explains that phentermine cannot be made by reductive amination.

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