Chapter 25.3, Problem 12CC

(a)

Interpretation Introduction

Interpretation:

The reagents for making the given amino acids using Hell-Volhard-Zelinsky reaction need to be identified.

Concept introduction:

$\alpha$-bromination of carboxylic acid in presence of bromine and a catalytic amount of phosphorous tribromide to form $\alpha$-bromocarboxylic acid is known as Hell-Volhard-Zelinsky reaction.  The formed $\alpha$-bromocarboxylic acid when treated with ammonia gives $\alpha$-aminocarboxylic acid as the product.

To identify: the reagents used for synthesis of leucine using Hell-Volhard-Zelinsky reaction.

(b)

Interpretation Introduction

Interpretation:

The reagents for making the given amino acids using Hell-Volhard-Zelinsky reaction need to be identified.

Concept introduction:

$\alpha$-bromination of carboxylic acid in presence of bromine and a catalytic amount of phosphorous tribromide to form $\alpha$-bromocarboxylic acid is known as Hell-Volhard-Zelinsky reaction.  The formed $\alpha$-bromocarboxylic acid when treated with ammonia gives $\alpha$-aminocarboxylic acid as the product.

To identify: the reagents used for synthesis of alanine using Hell-Volhard-Zelinsky reaction.

(c)

Interpretation Introduction

Interpretation:

The reagents for making the given amino acids using Hell-Volhard-Zelinsky reaction need to be identified.

Concept introduction:

$\alpha$-bromination of carboxylic acid in presence of bromine and a catalytic amount of phosphorous tribromide to form $\alpha$-bromocarboxylic acid is known as Hell-Volhard-Zelinsky reaction.  The formed $\alpha$-bromocarboxylic acid when treated with ammonia gives $\alpha$-aminocarboxylic acid as the product.

To identify: the reagents used for synthesis of valine using Hell-Volhard-Zelinsky reaction.