Concept explainers
Interpretation:
The overall effect of caffeine on a signal which is mediated by cAMP should be determined.
Concept Introduction:
Stimulants: These are a group of drugs with many potential therapeutic uses, but also widely used and abused recreationally. Stimulants improve mood, enhance alertness and relieve depression.
Caffeine, Nicotine, Cocaine, Ecstasy … are some examples for stimulants.
cAMP is a cyclic
Enzymes are proteins that increase the
Secondary messengers are short lived intracellular signaling molecules. Elevated concentration of these type of messengers leads to rapid alteration in the activity of one or more cellular enzymes.
Phosphodiesterase is an enzyme that breaks a phosphodiester bond. This enzyme plays a key role in regulating intracellular levels of the second messenger cAMP and hence cell function.
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Fundamentals of General, Organic, and Biological Chemistry (8th Edition)
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