Anatomy and Physiology by OpenStax
17th Edition
ISBN: 9781506698021
Author: J. Gordon Betts;Dean H. Kruse;Kelly A. Young;Peter DeSaix;Brandon Poe;Oksana Korol;James A. Wise;Eddie Johnson;Jody E. Johnson;Mark Womble
Publisher: XANEDU PUBLISHING
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Textbook Question
Chapter 28, Problem 28RQ
Marfan syndrome is inherited in an autosomal dominant pattern. Which of the following is true?
- Female offspring are more Likely to be carriers of the disease.
- Male offspring are more likely to inherit the disease.
- Male and female offspring have the same likelihood of inheriting the disease.
- Female offspring are more likely to inherit the disease.
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Among the following, which inheritance pattern increases the occurrence of the
disease?
Autosomal dominant
Sex linked dominant
Mitochondrial
O Autosomal recessive
In autosomal dominant disorders, the recurrence risk is ¾(75%) when one affected parent and one carrier parent produce an offspring . True or false
Q1: What is the probability that a child with one parent who has an autosomal dominant disorder will inherit the disease? Q2: Why are there no carriers with a dominant genetic disorder? Q3: Because dominant genetic disorders are rare, it is extremely rare for both parents to have the condition (genotype Aa). Draw a Punnett square with two Aa parents. What proportion of the offspring would have the disorder? What proportion would be normal?
Chapter 28 Solutions
Anatomy and Physiology by OpenStax
Ch. 28 - View this time-lapse movie...Ch. 28 - Visit this site...Ch. 28 - Sperm and ova are similar in terms of ________....Ch. 28 - Although the male ejaculate contains hundreds of...Ch. 28 - As sperm first reach the oocyte, they will contact...Ch. 28 - Fusion of pronuclei occurs during ________....Ch. 28 - Sperm must first complete ________ to enable the...Ch. 28 - Cleavage produces daughter cells called ________....Ch. 28 - The conceptus, upon reaching the uterus, first...Ch. 28 - The inner cell mass of the blastocyst is destined...
Ch. 28 - Which primary germ layer gave rise to the cells...Ch. 28 - What would happen if the trophoblast did not...Ch. 28 - During what process does the amnion envelop the...Ch. 28 - The placenta is formed from ________. the embryos...Ch. 28 - The foramen ovale causes the fetal circulatory...Ch. 28 - What happens to the urine excreted by the fetus...Ch. 28 - During weeks 9–12 of fetal development,...Ch. 28 - Progesterone secreted by the placenta suppresses...Ch. 28 - Which of the following is a possible culprit of...Ch. 28 - How does the decrease in progesterone at the last...Ch. 28 - Which of these fetal presentations is the easiest...Ch. 28 - Which of these shunts exists between the right and...Ch. 28 - Why is brown fat important? It is the newborns...Ch. 28 - Constriction of umbilical blood vessels during...Ch. 28 - Alveoli are connected to the lactiferous sinuses...Ch. 28 - How is colostrum most important to a newborn? It...Ch. 28 - Mature breast milk ________. has more sodium than...Ch. 28 - Marfan syndrome is inherited in an autosomal...Ch. 28 - In addition to codominance, the ABO blood group...Ch. 28 - Zoe has cystic fibrosis. Which of the following is...Ch. 28 - Darcy and Raul are having difficulty conceiving a...Ch. 28 - Sherrise is a sexually active college student. On...Ch. 28 - Approximately 3 weeks after her last menstrual...Ch. 28 - The Food and Nutrition Board of the Institute of...Ch. 28 - What is the physiological benefit of incorporating...Ch. 28 - Why would a premature infant requite supplemental...Ch. 28 - Devin is 35 weeks pregnant with her first child...Ch. 28 - Janine is 41 weeks pregnant with her first child...Ch. 28 - Describe how the newborns fust breath alters the...Ch. 28 - Newborns are at much higher risk for dehydration...Ch. 28 - Describe the transit of breast milk from...Ch. 28 - A woman who stopped breastfeeding suddenly is...Ch. 28 - Explain why it was essential that Mendel perform...Ch. 28 - How can a female carrier of an X-linked recessive...
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- Marfan syndrome is transmitted by a dominant gene.State the probability that a child with an affected parentwill have the disorderarrow_forwardIn humans, hemophilia is a sex-linked trait. Females can be normal, carriers, or have the disease. Males will either have the disease or not (but they won’t ever be carriers). X H X H = female, non-hemophilic X H X h = female, carrier X h X h = female, hemophilia X H Y = male, non-hemophilic X h Y= male, hemophiliac a.) Show the cross of a man who has hemophilia with a woman who is a carrier. What is the probability that their children will have the disease? b.) A woman who is a carrier marries a non-hemophilic man. Show the cross. What is the probability that their children will have hemophilia? What sex will a child in the family with hemophilia be? c.) A woman who has hemophilia marries a non-hemophilic man. How many of their children will have hemophilia, and what is their sex?arrow_forward2. STATEMENT: A woman and man both do not have sickle-cell anemia, but both had one parent who had sickle cell. Sickle-cell is an autosomal (somatic) recessive trait. a) What is the genotype for the woman, man and each of their parents? b) This couple unexpectedly is going to have their first child. i. What's the probability that their child will have not have sickle cell like the couple? ii. What's the probability that the child will have sickle cell like one the grandparents?arrow_forward
- What is Down's syndrome? Give its symptoms and cause. Why is it that the chances of having a child with Down's syndrome increases if the age of the mother exceeds forty years?arrow_forwardA patient has two parents with Huntington's disease. They may not have inherited this autosomal dominant disorder due to: 1) increased DNA repeats (CAG) during spermatogenesis 2) incomplete penetrance 3) inheriting one recessive allelearrow_forwardWhy is the chances of having a child with down's syndrome increases if the age of mother exceed forty year?arrow_forward
- A couple are both phenotypically normal but their son suffers from hemophilla, a sex linked recessive disorder. What fraction of their children are likely to suffer from hemophilia. what fraction are likely to be carriers.arrow_forwardIt is determined that Elsa is experiencing beta-thalassemia major. Which of the following statements is NOT true regarding this diagnosis? The cause of beta-thalassemia is genetic. Beta-thalassemia major is a grave condition and has a high mortality rate. Beta-thalassemia major is often treated with blood transfusions. Because beta-thalassemia is an x-linked trait, it affects males more often than females.arrow_forwardGenetic disorders Complete the following statements to describe several genetic disorders and their symptoms. Choices can be used more than once. The disorder called causes blue-colored skin, sickle-cell disease osteogenesis imperfecta The disorder called that leads to weakened, brittle bones. causes defective collagen methemoglobinemia autosomal dominant The disorder called causes abnormally thick mucus in the bronchial tubes and pancreatic ducts. autosomal recessive The disorder called leads to progressive cystic fibrosis degeneration of neurons in the brain. alkaptonuria The disorder called causes urine to be black. Huntington disease acer %23 24 & 4 8. 9. e y u < 6arrow_forward
- Children with this condition has the following features: wide or web-like neck; low-set ears; broad chest with widely spaced nipples; high, narrow roof of the mouth (palate); arms that turn outward at the elbows; fingernails and toenails that are narrow and turned upward; swelling of the hands and feet, especially at birth; slightly smaller than average height at birth; slowed growth; and cardiac defects. The statement applies to Turner syndrome only The statement applies to Down syndrome only The statement applies to both Turner syndrome and Down syndrome The statement applies to neither Turner syndrome nor Down syndromearrow_forwardWhat is the most likely mode of inheritance for the disease depicted in the following pedigree? I II III 1 1 2 1 2 autosomal recessive autosomal dominant 3 3 2 4 4 5 5 6arrow_forwardHemophilia is due to a sex-linked gene. It is recessive and found on the X chromosome. A woman who is a carrier for hemophilia marries a normal man. What will be the possible phenotypes of their children? (use the letter “H”)arrow_forward
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