ANATOMY & PHYSIOLOGY: AN INTEGRATIVE APP
3rd Edition
ISBN: 9781266163654
Author: McKinley
Publisher: MCG
expand_more
expand_more
format_list_bulleted
Concept explainers
Question
Chapter 29, Problem 3CSL
Summary Introduction
To determine:
The possibility that Simon and Carla will develop a Huntington disease.
Introduction:
Huntington disease is an autosomal recessive disease that can lead to many neurological degeneration and death of an individual, generally within 5 years of diagnosis.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
You met with two parents whose first child has sickle cell anemia. (The parents show no signs of the disease themselves). The mother comes to you in the third month of her second pregnancy, and wants to know if this child will also inherit the disease. As a genetics counselor, you are ready to evaluate this couple’s case by doing the following:1. Determine what the genotype of each parent is. Is this disease autosomal or sex-linked? Dominant or recessive?
A woman who is eight (8) weeks pregnant requests a direct test for Huntington’s disease on her fetus. She tells her geneticist that she wants the test because she recently discovered that there is a family history of the disease in her husband’s family. One of his parents is affected so he is at 50% risk of developing the condition. She is adamant that she does not want to give birth to a baby who is at risk of developing Huntington’s and says that the test will help her to ensure that this is not the case. In counseling, she reveals that she has discussed this issue several times with her husband but he has always said he is not willing to take a test. He does not want to know his status and is extremely anxious about the possibility that he might develop the condition. The woman and her husband are currently separated but are seeing a relationship counselor and trying to work things out. Despite this, the woman says they tend to fight a lot. When it is explained to her in counseling…
Mark has an autosomal recessive condition called sickle cell anemia, a serious blood disorder that is associated with painful complications. His spouse has not experienced symptoms of sickle cell anemia but their first child developed the disease. What conclusions can be drawn about the mother's genotype and the probability of having a second child with the condition? Answer Choices: A: her genotype is heterozygous and there is a 25% percent chance of having another child with the disorder B: her genotype is heterozygous and there is a 50% percent chance of having another child with the disorder C: her genotype is heterozygous and there is a 75% percent chance of having another child with the disorder D: she lacks the allele for sickle cell anemia in that she lacks symptoms of the disease. There is a 0% percent chance of having another child with the disorderMark has an autosomal recessive condition called sickle cell anemia, a serious blood disorder that is associated with…
Chapter 29 Solutions
ANATOMY & PHYSIOLOGY: AN INTEGRATIVE APP
Ch. 29.1 - Prob. 1LOCh. 29.1 - What distinguishes the pre-embryonic period from...Ch. 29.2 - Prob. 2LOCh. 29.2 - Prob. 3LOCh. 29.2 - Prob. 1WDTCh. 29.2 - Prob. 2WDLCh. 29.2 - Prob. 3WDLCh. 29.2 - Prob. 4LOCh. 29.2 - Prob. 5LOCh. 29.2 - How many cells are present initially in the...
Ch. 29.2 - Prob. 5WDLCh. 29.2 - Prob. 6LOCh. 29.2 - Prob. 7LOCh. 29.2 - Prob. 6WDLCh. 29.2 - Prob. 7WDLCh. 29.2 - Prob. 8LOCh. 29.2 - Prob. 9LOCh. 29.2 - What are the two cell layers of the bilaminar...Ch. 29.2 - Which cell layers give rise to each of the three...Ch. 29.2 - Prob. 10LOCh. 29.2 - Prob. 11LOCh. 29.2 - Prob. 10WDLCh. 29.3 - Prob. 12LOCh. 29.3 - Prob. 13LOCh. 29.3 - Prob. 11WDLCh. 29.3 - Prob. 14LOCh. 29.3 - Prob. 15LOCh. 29.3 - Prob. 12WDLCh. 29.3 - Prob. 13WDLCh. 29.3 - LEARNING OBJECTIVE
16. Define organogenesis and...Ch. 29.3 - Why is it important for a pregnant woman to...Ch. 29.4 - LEARNING OBJECTIVE
17. Describe the major events...Ch. 29.4 - Prob. 15WDLCh. 29.5 - LEARNING OBJECTIVE
18. Compare and contrast the...Ch. 29.5 - WHAT DID YOU LEARN?
16 What are some of the...Ch. 29.5 - LEARNING OBJECTIVE
19. Discuss the critical...Ch. 29.5 - Prob. 20LOCh. 29.5 - How do estrogen and progesterone act to sustain...Ch. 29.5 - What are the actions of CRH, HPL, oxytocin, and...Ch. 29.5 - Prob. 21LOCh. 29.5 - Prob. 22LOCh. 29.5 - Prob. 2WDTCh. 29.5 - Prob. 19WDLCh. 29.5 - Prob. 20WDLCh. 29.5 - Prob. 23LOCh. 29.5 - Prob. 24LOCh. 29.5 - Prob. 21WDLCh. 29.5 - Prob. 22WDLCh. 29.5 - Prob. 25LOCh. 29.5 - Prob. 26LOCh. 29.5 - Prob. 23WDLCh. 29.5 - Prob. 24WDLCh. 29.5 - Prob. 27LOCh. 29.5 - Prob. 25WDLCh. 29.6 - LEARNING OBJECTIVE
28. Explain the physiologic...Ch. 29.6 - How do progesterone, estrogen, and oxytocin...Ch. 29.6 - LEARNING OBJECTIVE
29. List the signs and...Ch. 29.6 - Prob. 27WDLCh. 29.6 - LEARNING OBJECTIVE
30. Explain the signs and...Ch. 29.6 - LEARNING OBJECTIVE
31. Describe the positive...Ch. 29.6 - Prob. 28WDLCh. 29.6 - Prob. 29WDLCh. 29.6 - Prob. 32LOCh. 29.6 - Prob. 30WDLCh. 29.6 - Prob. 31WDLCh. 29.7 - Prob. 33LOCh. 29.7 - Prob. 34LOCh. 29.7 - Prob. 3WDTCh. 29.7 - Prob. 32WDLCh. 29.7 - Prob. 33WDLCh. 29.8 - Prob. 35LOCh. 29.8 - Prob. 34WDLCh. 29.8 - Prob. 36LOCh. 29.8 - Prob. 35WDLCh. 29.8 - Prob. 37LOCh. 29.8 - Prob. 4WDTCh. 29.8 - How does the positive feedback mechanism in...Ch. 29.8 - Prob. 38LOCh. 29.8 - Prob. 37WDLCh. 29.9 - Prob. 38WDLCh. 29.9 - Prob. 40LOCh. 29.9 - How does codominant inheritance differ from...Ch. 29.9 - Prob. 41LOCh. 29.9 - Prob. 40WDLCh. 29.9 - Prob. 42LOCh. 29.9 - Prob. 41WDLCh. 29 - _____ 1. The outer layer of the blastocyst that...Ch. 29 - _____ 2. At about day 3 after fertilization, the...Ch. 29 - During gastrulation, cells from the _____ layer of...Ch. 29 - ______ 4. The cells of the embryoblast...Ch. 29 - _____ 5. Which of the following is not an...Ch. 29 - _____ 6. All of the following cardiovascular...Ch. 29 - _____ 7. After a woman gives birth, what happens...Ch. 29 - _____ 8. Freckles are considered to be a dominant...Ch. 29 - _____ 9. Skin color is a trait that is determined...Ch. 29 - A woman is a carrier for the color-blindness gene,...Ch. 29 - Briefly describe the process of fertilization,...Ch. 29 - List the five regions of the mesoderm, and...Ch. 29 - Explain why teratogens are especially harmful to...Ch. 29 - Describe the differences between the embryonic...Ch. 29 - Prob. 15DYBCh. 29 - Prob. 16DYBCh. 29 - Prob. 17DYBCh. 29 - Describe the various ways by which the mothers...Ch. 29 - Compare and contrast strict dominant-recessive...Ch. 29 - Explain the difference between X-linked recessive...Ch. 29 - Prob. 1CALCh. 29 - Ashley is a 29-year-old pregnant woman who is in...Ch. 29 - Ashley is a 29-year-old pregnant woman who is in...Ch. 29 - Prob. 4CALCh. 29 - Ashley is a 29-year-old pregnant woman who is in...Ch. 29 - Prob. 1CSLCh. 29 - Prob. 2CSLCh. 29 - Prob. 3CSL
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- A patient has two parents with Huntington's disease. They may not have inherited this autosomal dominant disorder due to: 1) increased DNA repeats (CAG) during spermatogenesis 2) incomplete penetrance 3) inheriting one recessive allelearrow_forwardThe father of three sons and two daughters begins to show symptoms of Huntington disease. What is the probability that Sam, the man’s second oldest son (II-2), will suffer from the disease if he lives a normal life span? Sam’s mother and her ancestors do not have the disease. Sam's father was adopted, so we do not know his biological family history for Huntington disease. Explore all possible outcomes for Sam and explain your reasoning. What about the risk to Sam's sisters? Would that be the same or not?arrow_forwardAnswer the question(s) in reference to the five disorders listed below: Hutchtinson-Gilford progeria hemophilia turner syndrome down syndrome klinefelter syndromearrow_forward
- At her first prenatal visit, a woman relates that her maternal aunt has cystic fibrosis, an autosomal recessive illness. Which of the following statements is appropriate for the nurse to make? a. It is unnecessary for you to worry since our aunt is not a direct relation." b. "We can check to see whether or not you are a carrier for cystic fibrosis." c. "You should have an amniocentesis to see whether or not your child has the disease." d. Please ask your mother whether she has ever had any symptoms of cystic fibrosisarrow_forwardThe father of three sons and two daughters begins to show symptoms of Huntington's disease. What is the probability that Sam, the man’s second oldest son (II-2), will suffer from the disease if he lives a normal life span? Sam’s mother and her ancestors do not have the disease. Sam's father was adopted, so we do not know his biological family history for Huntington disease. Explore all possible outcomes for Sam and explain your reasoning. What about the risk to Sam's sisters? Would that be the same or not?arrow_forwardHuntington disease (HD) is a genetic disorder that usually first appears in middle age and, over time, leads to involuntary movements, impaired speech, difficulty swallowing and speaking, and cognitive decline. There is no cure for HD, and affected individuals eventually die, usually after 10 to 15 years of progressively worsening symptoms. Huntington disease is inherited as an autosomal dominant disorder. Presymptomatic genetic testing for HD is available for people with a family history of the disease. Individuals who have a parent with HD have a 50% chance of inheriting the HD gene and eventually having HD. Some of these individuals want to know if they will eventually get the disease, and they undergo presymptomatic genetic testing. Others do not want to know, given that there is no cure or effective treatment for the disease. If you were at risk for HD, would you want to undergo genetic testing? What are some reasons for and against having a genetic test for HD?arrow_forward
- Because Elsa has received a confirmed diagnosis of beta-thalassemia major, which of the following statements is true about her parents? Only her mother carried the gene that caused her blood disorder. Only her father carried the gene that caused her blood disorder. If her parents have another child naturally, there is a 100% chance that the second child will be diagnosed with beta-thalassemia major. If her parents have another child naturally, there is a 25% chance that the second child will be diagnosed with beta-thalassemia major.arrow_forwardHuntington's disease is characterized by late onset mental deterioration and is invariably fatal. It appears to be caused by an autosomal dominant gene. A man with Huntington's disease (heterozygous) marries a normal woman and they have 5 children. What risk does each child have of contracting the disease? Write the full punnett sqaure equation showing ALL steps used to achieve your answer.arrow_forwardA form of hemophilia is caused by a sex-linked (X-linked) recessive gene. A phenotypically normal woman whose father had hemophilia marries a man who suffers with hemophilia. What is the probability that their first daughter will have hemophilia?arrow_forward
- Hereditary hemochromatosis is an autosomal recessive genetic disorder that causes the body to absorb too much iron from the diet. This excess iron is stored in the body's tissues and organs, particularly the skin, heart, liver, pancreas, and joints. Because humans cannot increase the excretion of iron, excess iron can overload and eventually damage tissues and organs. A young couple, Bart and Jenny, are expecting a child and are aware there might be a chance that their child could be affected by this disorder. Jenny (the wife) has ichthyosis, but Bart (her husband) is unaffected and completely normal with respect to the allele responsible for this disorder. Both Bart and Jenny were Biology majors as undergraduates. Knowing a little about the pattern of X-linked recessive inheritance, Bart and Jenny were concerned when ultrasound revealed that they would be having a son. However, genetic testing performed on the baby shortly after birth revealed that their newborn son, Mark, did not…arrow_forwardNeurofibromatosis-1 (NF1) is an autosomal dominant disorder where tumours form in the base layer of the skin or in nerve tissues. What is the probability that individuals II-1 and II-2 will have a genetic son with NF1? Find the image attached.arrow_forwardJonah and Jana are siblings. Jonah has the genetic disorder cystic fibrosis, caused by inheriting two mutant alleles of the CFTR gene (the gene that when mutant causes cystic fibrosis) - one allele was inherited from each parent. Jana does not have cystic fibrosis. Which of the following statements is/are true? Jana does not have the CFTR gene. Jana has two copies of the CFTR gene. Jana has at least one copy of the non-mutant allele of the CFTR gene. Jana has two copies of the mutant allele of the CFTR gene.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
How stress affects your body - Sharon Horesh Bergquist; Author: TED-Ed;https://www.youtube.com/watch?v=v-t1Z5-oPtU;License: Standard Youtube License