To explain:
The molecular biology of the antigenic shift in influenza viruses and comment on the immunological consequences for the host. Why does the antigenic shift prevent the production of a single universally effective vaccine to control influenza? Comparison of antigenic shift and antigenic drift and the causative agent of the greatest antigenic change. Which creates the biggest problems for vaccine developers and which can lead to pandemic influenza and why?
Introduction:
The process in which two or more different strains of the viruses or strains of two or more different viruses are combined together to form a new subtype is referred to as antigenic shift. The new subtype possesses a mixture of the surface antigens. The mechanism of variations in viruses which allows the accumulation of mutation within the genes coding for the specific antibody sites are termed as antigenic drifts.
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