EBK MICROBIOLOGY:W/DISEASES BY BODY...-
5th Edition
ISBN: 9780134608242
Author: BAUMAN
Publisher: PEARSON
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Textbook Question
Chapter 3, Problem 11TMW
Many antimicrobial drugs target bacterial cell walls. Why aren't there many drugs that act against bacterial cytoplasmic membranes?
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Students have asked these similar questions
The type of antimicrobial drug that would be most likely to have toxic effects in
humans based on the premise of selective toxicity when treating microbial infection
would be a drug that
O 1) inhibits the synthesis of the cell wall
O 2) inhibits metabolic pathways
O 3) disrupts the cytoplasmic membrane
4) inhibits protein synthesis
5) All of the above have equal potential to be toxic
Broad-spectrum drugs target a wide variety of bacterial pathogens. Even when the broad-spectrum drug is capable of killing a target pathogen, it may not be the best treatment.
Which statement best explains why a broad spectrum drug might be an undesirable treatment choice?
Broad-spectrum antimicrobials are usually toxic to the host cells.
Broad-spectrum antimicrobials only work if they are used shortly after the infection begins.
Broad-spectrum antimicrobials may kill much of the normal microbiota.
Broad-spectrum antimicrobials are not able to kill bacteria that are in their log phase of growth.
Broad-spectrum antimicrobials may stimulate excess growth of the normal microbiota.
Important characteristics of antimicrobial drugs include:
a) readily delivered to the site of infection
b) high toxicity against microbial cells
c) do not cause serious side effects in humans
d) remains active in body tissues and fluids
e) all of the above
Chapter 3 Solutions
EBK MICROBIOLOGY:W/DISEASES BY BODY...-
Ch. 3 - Prob. 1TMWCh. 3 - In 1985, an Israeli scientist discovered the...Ch. 3 - Why is a pilus a type of fimbria, but a flagellum...Ch. 3 - Why is the microbe illustrated in Figure 3.2 more...Ch. 3 - The Big Game College sophomore Nadia is a star...Ch. 3 - When the bacterium Escherichia coli is grown in a...Ch. 3 - Prob. 6TMWCh. 3 - Why do scientists consider bacterial and archaeal...Ch. 3 - Why did scientists in the 19th and early 20th...Ch. 3 - Why do some scientists consider archaea, which are...
Ch. 3 - Why are eukaryotic glycocalyces covalently bound...Ch. 3 - Many antimicrobial drugs target bacterial cell...Ch. 3 - Colchicine is a drug that inhibits microtubule...Ch. 3 - A cell may allow a large or charged chemical to...Ch. 3 - Which of the following statements concerning...Ch. 3 - A 9 + 2 arrangement of microtubules is seen in...Ch. 3 - Which of the following is most associated with...Ch. 3 - Which of the following is not associated with...Ch. 3 - Which of the following is true of Svedbergs? a....Ch. 3 - Which of the following statements is true? a. The...Ch. 3 - Prob. 8MCCh. 3 - Bacterial flagella are ______________. a. anchored...Ch. 3 - Prob. 10MCCh. 3 - A Gram-negative cell is moving uric acid across...Ch. 3 - Gram-positive bacteria _______________. a. have a...Ch. 3 - Endospores ________________. a. are reproductive...Ch. 3 - Prob. 14MCCh. 3 - Dipicolinic acid is an important component of...Ch. 3 - Match the structures on the left with the...Ch. 3 - Match the term on the left with its description on...Ch. 3 - Label the structures of the following prokaryotic...Ch. 3 - Label each type of flagellar arrangement.Ch. 3 - A scientist who is studying passive movement of...Ch. 3 - Describe (or draw) an example of diffusion down a...Ch. 3 - Sketch, name, and describe three flagellar...Ch. 3 - Prob. 3SACh. 3 - The term fluid mosaic has been used in describing...Ch. 3 - A local newspaper writer has contacted you, an...Ch. 3 - Prob. 6SACh. 3 - Compare bacterial cells and algal cells, giving at...Ch. 3 - Contrast a cell of Streptococcus pyogenes (a...Ch. 3 - Differentiate among pili, fimbriae, and cilia,...Ch. 3 - Prob. 10SACh. 3 - Prob. 11SACh. 3 - Prob. 12SACh. 3 - What is the function of glycocalyces and fimbriae...Ch. 3 - Prob. 14SACh. 3 - Compare and contrast three types of passive...Ch. 3 - Prob. 16SACh. 3 - Prob. 17SACh. 3 - Prob. 18SACh. 3 - Prob. 1CTCh. 3 - Methylene blue binds to DNA. What structures in a...Ch. 3 - Prob. 3CTCh. 3 - Prob. 4CTCh. 3 - A researcher carefully inserts an electrode into...Ch. 3 - Prob. 6CTCh. 3 - An electron micrograph of a newly discovered cell...Ch. 3 - An entry in a recent scientific journal reports...Ch. 3 - Prob. 9CTCh. 3 - Prob. 10CTCh. 3 - Prob. 11CTCh. 3 - Prob. 12CTCh. 3 - Prob. 13CTCh. 3 - Prob. 14CTCh. 3 - Using the following terms, fill in the following...
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- Given that both human cells and pathogens synthesize proteins at ribosomal sites, how can antimicrobial agents that target this process be safe to use in humans?arrow_forwardList all the antibiotics in the above table that work through destroying the bacterial cell wall. (if there are none listed please state that)arrow_forwardWhat bacterial structural target would make an antibacterial drug selective for gram-negative bacteria? Provide one example of an antimicrobial compound that targets this structure.arrow_forward
- Changes in the bacterial genome can lead to resistance to antimicrobialdrugs. what the different ways that these changes in the DNA occur?arrow_forwardAnswer all of the questions 1. Which of the following antimicrobial drugs target DNA/RNA synthesis? a) Ciprofloxacin b) Sulfa drugs c) Gentamycin d) Penicilline) Polymyxin B 2. Which of the following antimicrobial drugs target protein synthesis? a) Ciprofloxacin b) Sulfa drugs c) Gentamycin d) Penicilline) Polymyxin B 3. true or false: Streptococcus is killed by growing on blood agar.arrow_forwardSelective toxicity of a drug refers to a) damage to pathogenic organisms only b) damage to prokaryotic cell membranes c) damage to the target organisms but not the host cell d) easily broken down by the host and pathogen.arrow_forward
- Technically speaking, which antimicrobial drugs are produced naturally? Biofilms Antibiotics Semisynthetics Syntheticsarrow_forwardCould an organism that is susceptible to an antimicrobial agent in laboratory testing fail to respond to it when that drug is used to treat the patient? Explain.arrow_forwardSome bacteria produce the enzyme penicillinase, which breaks the beta-lactam ring in the penicillin molecule and converts it into penicilloic acid, which is harmless to bacteria. This is an example of which of the following mechanisms of antibiotic resistance? which option below is the answer? Destruction or inactivation of the antibiotic by the microbe Preventing penetration to the target site within the microbe Alteration of the drug’s target site(s) within the microbe None of the other four answers are correct Rapid ejection (pumping) of the drug out of the microbial cellarrow_forward
- Why might clinical medicine have an interest in understanding bacterial cell division at the molecular level? Explain why a hyperthermophile would probably not be a human pathogen. Describe four factors that may have an influence on the effectiveness of an antimicrobial treatment. Explain why 70% or 80% alcohol is more effective than 100% alcohol in controlling microorganisms.arrow_forwardIdentify examples of cell-wall antibiotics that are not beta-lactam drugs.arrow_forwardWhy is the effectiveness of an antimicrobial agent determined using an exponentially growing bacterial culture? Please explain.arrow_forward
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USMLE-Rx Antimicrobial Therapy; Author: USMLE-Rx;https://www.youtube.com/watch?v=Pka1Ynlrqtw;License: Standard Youtube License