Chapter 3, Problem 129EQ

1. Which of the following is the strongest nucleophile? Refer to the diagram below with an MeOH, MeSH, etc. 2. Which of the following is true about the stereochemistry of SN1 reaction?a.retention of configuration at the electrophilic centerb.50:50 mixture of retention and inversion of configuration at the electrophilic centerc.inversion of configuration at the electrophilic centerd. slightly more inversion than retention at the electrophilic center

odine monochloride, ICI, is a reagent whose reactivity mirrors that of other dihalogens (X₂) with nucleophilic πt bonds. Using curved arrows to show the flow of electrons, draw a plausible mechanism for the following transformation. Make sure that your mechanism accounts for the correct stereoselectivity.

Explain why 1-bromo-2,2-dimethylpropane has difficulty undergoing both SN2 and SN1 reactions. . Can it undergo E2 and E1 reactions?

What sequence of reagents can be used to accomplish the conversion shown below?

Explain the features of E1 reactions are worthy of note ?

What is the major neutral organic product for the following transformation?

In the reaction series below, write down the appropriate reagents that can be used where there are question marks.

Please provide a mechanism with curved arrows by replacing MgBr with 3-methoxyphenylmagnesium bromide and the final product should be 3-methoxybenzoic acid

A student wanted to know whether the greater proximity of the nucleophile to the C-2 carbon in the transition state is what causes the 1,2-addition product to be formed faster when 1,3-butadiene reacts with HCl. Therefore, she decided to investigate the reaction of 2-methyl-1,3-cyclohexadiene with HCl. Her friend told her that she should use 1-methyl-1,3-cyclohexadiene instead. Should she follow her friend’s advice?