ORGANIC CHEM W/CNCT+SOLUTION MANUAL >BI<
5th Edition
ISBN: 9781260293616
Author: SMITH
Publisher: MCG CUSTOM
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Question
Chapter 3, Problem 3.8P
Interpretation Introduction
Interpretation: The primary, secondary or tertiary amides in dolastatin are to be classified.
Concept introduction: Amides are the acid derivatives in which a nitrogen atom is bonded to an adjacent carbonyl carbon. They are synthesized by the reaction of an acid chloride with an amine. Amides are produced when esters react with
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Students have asked these similar questions
Classify the amides in dolastatin, an anticancer compound isolated from the Indian seahare Dolabella auricularia, as 1°, 2°, or 3°.
2. What is produced when an amine reacts with a strong acid such as HCl?
A. An amine and the OH- ion
B. An amide and the H+ ion
C. An ammonium hydroxide
D. An ammonium salt
which is false?
Enantiomers of amines are separable (resolvable).
Amines are chiral.
Shape of amines is trigonal pyramid.
N in amines is sp3 hybridized.
Chapter 3 Solutions
ORGANIC CHEM W/CNCT+SOLUTION MANUAL >BI<
Ch. 3 - Prob. 3.1PCh. 3 - (a) Classify the carbon atoms in each compound as...Ch. 3 - Problem 3.3 Classify a carbon atom by the number...Ch. 3 - Classify each alkyl halide and alcohol as , or...Ch. 3 - Prob. 3.5PCh. 3 - Prob. 3.6PCh. 3 - Draw the structure of a compound of molecular...Ch. 3 - Prob. 3.8PCh. 3 - Prob. 3.9PCh. 3 - Draw the structure of a compound fitting each...
Ch. 3 - Draw structures that fit each description and name...Ch. 3 - What types of intermolecular forces are present in...Ch. 3 - Which compound in each pair has the higher boiling...Ch. 3 - Explain why the boiling point of propanamide, is...Ch. 3 - Predict which compound in each pair has the higher...Ch. 3 - Prob. 3.16PCh. 3 - Which compounds are water soluble? a. b. c.Ch. 3 - a Label the hydrophobic and hydrophilic portions...Ch. 3 - Prob. 3.19PCh. 3 - Prob. 3.20PCh. 3 - Prob. 3.21PCh. 3 - Prob. 3.22PCh. 3 - Problem 3.23 (a) What types of intermolecular...Ch. 3 - Prob. 3.24PCh. 3 - Prob. 3.25PCh. 3 - Problem 3.26 Label the electrophilic and...Ch. 3 - Problem 3.27 Considering only electron density,...Ch. 3 - Prob. 3.28PCh. 3 - 3.29
Identify the functional groups in the...Ch. 3 - Prob. 3.30PCh. 3 - 3.31 For each alkane: (a) classify each carbon...Ch. 3 - 3.32 Identify the functional groups in each...Ch. 3 - 3.33 Identify each functional group located in the...Ch. 3 - 3.34 (a)Identify the functional groups in...Ch. 3 - Draw seven constitutional isomers with molecular...Ch. 3 - Prob. 3.36PCh. 3 - Prob. 3.37PCh. 3 - Prob. 3.38PCh. 3 - Intramolecular force of attraction are often...Ch. 3 - 3.40 (a) Draw four compounds with molecular...Ch. 3 - 3.41 Rank the compounds in each group in order of...Ch. 3 - Explain why CH3CH2NHCH3 has higher boiling point...Ch. 3 - Prob. 3.43PCh. 3 - 3.44 Rank the following compounds in order of...Ch. 3 - Prob. 3.45PCh. 3 - 3.46 Rank the following compounds in order of...Ch. 3 - 3.47 Which of the following molecules can hydrogen...Ch. 3 - 3.48 Explain why diethylether and have similar...Ch. 3 - Prob. 3.49PCh. 3 - 3.50 Predict the solubility of each of the...Ch. 3 - Prob. 3.51PCh. 3 - Prob. 3.52PCh. 3 - 3.53 THC is the active component in marijuana, and...Ch. 3 - Prob. 3.54PCh. 3 - Prob. 3.55PCh. 3 - 3.56 Label the electrophilic and nucleophilic...Ch. 3 - 3.57 By using only electron density arguments,...Ch. 3 - 3.58 The composition of a cell membrane is not...Ch. 3 - Prob. 3.59PCh. 3 - 3.60 Quinapril (trade name Accupril) is a drug...Ch. 3 - 3.61 Answer each question about oxycodone, a...Ch. 3 - Prob. 3.62PCh. 3 - Prob. 3.63PCh. 3 - 3.64 Explain why A is less water soluble than B,...Ch. 3 - 3.65 Recall from section 1.10B that there is...
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Similar questions
- a.Primary amides tend to exist as dimers in the solid and liquid state. b.Dimethylacetamide, CH3CON(CH3)2 has a higher boiling point than acetamide. c.Nitrile is often classified as an acid derivative because it is hydrolyzed to a -COOH. d.Esters have lower boiling points than ketones of comparable molecular masses. Whice are correct?arrow_forwardBecause amines are basic, they can often accept a proton. Draw the protonated structure of n-propylamine.arrow_forward2. What is produced when an amine reacts with water? A. A primary alcohol and ammonia B. An amide and a hydrogen (H+) ion C. An ammonium ion and a hydroxide (OH-) ion D. An amide and a hydroxide (OH-) ionarrow_forward
- Complete equations for the hydrolysis of the amides in concentrated aqueous NaOH. Show all products as they exist in aqueous NaOH and the number of moles of NaOH required for hydrolysis of each amide.arrow_forwardHinsberg's Method to determine, 1°, 2°, 3° amines. Draw the structure of the products of the following reactions. Aniline (1°) + BSC, excess NaOH (DRAW STRUCTURE), then + HCl (DRAW STRUCTURE) Diethylamine (2°)+ BSC, excess NaOH (DRAW STRUCTURE), then + HCl (DRAW STRUCTURE) Triethylamine (3°)+ BSC, excess NaOH(DRAW STRUCTURE), then + HCl (DRAW STRUCTURE)arrow_forwardDraw and name compounds that meet the following descriptions: a. Two primary, 2 secondary, and 2 tertiary amines having the formula C5H13Narrow_forward
- Arrange the following amines in order of increasing boiling point, lowest bp to highest bp:(CH3)2CHCH2CH2NH2, (CH3)2CHN(CH3)2, and (CH3)2CHCH2NHCH3.arrow_forwardPredict the major products formed when the following amines undergo exhaustivemethylation, treatment with Ag2O, and heating.N-ethylpiperidinearrow_forwardWhich type of amine is phentermine? a) a primary aliphatic amine b) a primary aromatic amine c) a tertiary aliphatic amine d) a tertiary aromatic aminearrow_forward
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