ORGANIC CHEMISTRY-ACCESS
ORGANIC CHEMISTRY-ACCESS
6th Edition
ISBN: 9781260475586
Author: SMITH
Publisher: MCG
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Chapter 3, Problem 63P

Quinapril (trade name Accupril) is a drug used to treat hypertension and congestive heart

failure.

Chapter 3, Problem 63P, 3.60 Quinapril (trade name Accupril) is a drug used to treat hypertension and congestive heart

a. Identify the functional groups in quinpril.

b. Classify any alcohol, amide or amine as 1 ° 2 ° or 3 ° .

c. At which sites can quinapril hydrogen bond to water?

d. At which sites can quinapril hydrogen bond to acetone [ ( CH 3 ) 2 CO ] ?

e. Label the most acidic hydrogen atom.

f. Which site is most basic?

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V. Classify each amine as 1', 2 or 3'. Give the IUPAC name for each amine. CH3 a. CH3CHCH,CH2NHCH3 b. CH3-C-CH,NH2 ČH3 ČH3
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Classify each amine as 1˚, 2˚, or 3˚. Give the IUPAC name for each amine.

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