CONNECT W/APR & PHILS FOR FOX HUMAN PHYS
15th Edition
ISBN: 9781265397586
Author: Fox
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Textbook Question
Chapter 3, Problem 9CP
Draw a simple diagram of the semiconservative replication of DNA using stick figures and two colors.
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Label all of the lettered components (A through H) in the figure of DNA replication below.
C
A
G
E
Sort the phrases into the appropriate bins depending on which protein they describe.
1) Binds at the replication fork
2) binds after the replication fork
3) binds ahead of the replication fork
4) breaks H-bonds between bases
5) prevents H-bonds between bases
6) breaks covalent bonds in DNA backbone
Helicase:
Topoisomerase:
Single-strand binding protein:
Below is a diagram of DNA replication as currently believed to occur in E. coli. Arrows start from numbers and end at specific points. Answer the questions relating to the locations specified by the numbers
(1) Which end (5' or 3') of the molecule is here?
(2) Which enzyme is probably functioning here to deal with supercoils in the DNA?
(3) Which enzyme is probably functioning here to unwind the DNA?
Chapter 3 Solutions
CONNECT W/APR & PHILS FOR FOX HUMAN PHYS
Ch. 3 - According to the fluid-mosaic model of the plasma...Ch. 3 - After the DNA molecule has replicated itself, the...Ch. 3 - Nerve and skeletal muscle cells in the adult,...Ch. 3 - Prob. 4RACh. 3 - The phase of mitosis in which the chromatids...Ch. 3 - Prob. 6RACh. 3 - Which of these statements about RNA is true?...Ch. 3 - Prob. 8RACh. 3 - Prob. 9RACh. 3 - Prob. 10RA
Ch. 3 - Prob. 11RACh. 3 - Which of these statements about tRNA is true?...Ch. 3 - The step in protein synthesis during which tRNA,...Ch. 3 - Prob. 14RACh. 3 - Prob. 15RACh. 3 - Prob. 16RACh. 3 - Give some specific examples that illustrate the...Ch. 3 - Describe the structure of nucleosomes, and explain...Ch. 3 - What is the genetic code, and how does it affect...Ch. 3 - Why may tRNA be considered the "interpreter" of...Ch. 3 - Prob. 21RACh. 3 - Define the terms genome and proteome, and explain...Ch. 3 - Prob. 23RACh. 3 - Explain the functions of centrioles in nondividing...Ch. 3 - Prob. 25RACh. 3 - Prob. 26RACh. 3 - Define apoptosis and explain the physiological...Ch. 3 - Describe what is meant by epigenetic inheritance,...Ch. 3 - Discuss the role of chromatin proteins in...Ch. 3 - Explain how p53 functions as a tumor suppressor...Ch. 3 - Prob. 31RACh. 3 - Antibiotics can have different mechanisms of...Ch. 3 - Explain how it is possible for the human proteome...Ch. 3 - Explain RNA interference RNAi by siRNA and miRNA...Ch. 3 - Describe the function and significance of...Ch. 3 - Prob. 36RACh. 3 - Review figure 3.19 and answer the following...Ch. 3 - Prob. 38RACh. 3 - Describe the structure of the plasma membrane.Ch. 3 - Describe the structure and function of cilia,...Ch. 3 - Prob. 2aCPCh. 3 - Prob. 2bCPCh. 3 - Prob. 3aCPCh. 3 - Prob. 3bCPCh. 3 - Describe the structure and functions of...Ch. 3 - Prob. 3dCPCh. 3 - Describe the structure and function of ribosomes.Ch. 3 - Distinguish the two types of endoplasmic reticulum...Ch. 3 - Describe the appearance and composition of...Ch. 3 - Explain how RNA is produced within the nucleus...Ch. 3 - Explain how precursor mRNA is modified to produce...Ch. 3 - Explain how mRNA. rRNA, and tRNA function during...Ch. 3 - Describe the rough endoplasmic reticulum, and...Ch. 3 - Describe post-translational changes and other...Ch. 3 - Draw a simple diagram of the semiconservative...Ch. 3 - Describe the cell cycle using the proper symbols...Ch. 3 - Prob. 10bCPCh. 3 - List the phases of mitosis and briefly describe...Ch. 3 - Distinguish between mitosis and meiosis, describe...
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- Using the illustration of DNA replication given below label the following:arrow_forwardDraw a replication origin in E. coli. Place the first 4 primers in the figure. Show how the replication would proceed. Label polarity of ALL template and growing (newly synthesized) strands. Show direction of synthesis on all growing strands and identify all leading and lagging strands (I do not want you to mention or describe the enzymes involved). please give answer asaparrow_forwardThe following statements are correct EXCEPT: A) Information in the DNA is transcribed int mRNA and translated into proteins B) Information in the DNA is translated int mRNA and transcribed into proteins C) Information in the DNA is copied by DNA polymerase D) The lagging strand during DNA replication is synthesized continuously to form the okazaki fragments E) B and Darrow_forward
- Describe how continuous replication proceeds. Describe how discontinuous replication proceeds.arrow_forwardThe Escherichia coli chromosome is a circular DNA molecule and contains a single origin of replication. List the mechanistic steps that can terminate the movement of replication forks in this chromosome.arrow_forwardDescribe the structure of a bacterial genome, and explain how it differs from a eukaryotic genome. Explain what a plasmid is, and describe the role of plasmids in the spread of antibiotic resistance genes. Explain how bidirectional semiconservative DNA replication copies the circular chromosome of a bacterium during cell division. Explain the steps of replication by DNA polymerase, including initiation, elongation, and termination. Explain the different kinds of mutations and how they occur.arrow_forward
- Look at the double-stranded segment of DNA shown below. Imagine that the two strands have already been denatured, and the temperature has been decreased to an appropriate annealing temperature. Show where the two primers would anneal to the strands, then indicate the direction of extension on each new strand with an arrow. 5’--T C A G G A C G T A A G C T T G C A T A T C T C G A T G C T A A A T C A T—3’ 3’--A G T C C T G C A T T C G A A C G T A T A G A G C T A C G A T T T A G T A—5’ Primer #1: 3’ A C G A T T T 5’ Primer #2: 5’ G G A C G T A 3’arrow_forwarda) Under normal conditions E. coli produces three DNA polymerases. State their functional similarities and differences. b) List the other proteins and enzymes involved in DNA replication in E.coli and give their functions.arrow_forwardA region of DNA has six copies of a trinucleotide repeat. During one round of replication, the template strand slips as shown in the diagram. How many repeats will the DNA have if the newly synthesized strand is used as a template in the next round of replication? 1 5'-CAG 3'-GTC GTC 4 2 GTCH 3 2 CAG CAG GTC 3 GTC 5 4 CAG-3' GTC -5' 6 Next round of DNA replicationarrow_forward
- Using the following DNA sequence what would be the complementary DNA made during replication? TAC GCG TTA CGA ATCarrow_forwardIn one, simple sentence define the function of the following 1. Helicase = 2. Alpha subunit of DNA polymerase III =arrow_forwardIndicate the proteins involved in the following steps of DNA replication in E. coli a. ___________ initiator of replication by binding to the origin of replication of the prokaryote ___________ a dimer that unzips the DNA helix ___________ an enzyme responsible for relieving positive supercoils ahead of replication fork ___________ maintains DNA in single-stranded state ___________ primary replicating enzyme ___________ synthesizes RNA primers The resulting gap by removal of RNA primer is filled in by ___________. h. the resulting nick is sealed by _____________.arrow_forward
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