Campbell Biology in Focus; Modified Mastering Biology with Pearson eText -- ValuePack Access Card -- for Campbell Biology in Focus (2nd Edition)
2nd Edition
ISBN: 9780134433776
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman
Publisher: PEARSON
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Chapter 35, Problem 10TYU
Summary Introduction
To determine:
The feasibility of treating septic shock with the drug that blocks the TLR signaling using mutated mice that has mutation that cause the inactivation of the TLR gene and purified LPS.
Introduction:
TLR are the toll like receptors that are involved in the septic shock of the body that is induced by the lipopolysaccharides (LPS) of the gram negative bacteria when it is introduced into the blood. The TLR are the reason for the septic shock.
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SCIENTIFIC INQUIRY A major cause of septic shock is thepresence of lipopolysaccharide (LPS) from bacteria in the blood.Suppose you have available purified LPS and several strains ofmice, each with a mutation that inactivates a particular TLRgene. How might you use these mice to test the feasibility oftreating septic shock with a drug that blocks TLR signaling?
a major cause of septic shock is the presence of lipopolysaccharide (LPS) from bacteria in the blood. suppose you have available purified LPS and several strain of mice, each with a mutation that inactivates a particular TLR gene. How might you use these mice to test the feasibility of treating septic shock with a drug that blocks TLR signaling?
Which of the following is true about innate immune system? Check all that apply.
PAMPs recognize pathogen recognition receptors (PRRs) such as TLRs, NLRs and RLRs present on/in host cells
TLRs that are expressed on cell surface are mostly recognized by viruses, whereas intracellular TLRs are recognized by bacteria
PRRs can induce inflammatory response, opsonization and phagocytosis
Pattern associated molecular patterns (PAMPs) are molecules such as CpG DNA, cytosolic dsDNA and RNAs made by the host cell
Chapter 35 Solutions
Campbell Biology in Focus; Modified Mastering Biology with Pearson eText -- ValuePack Access Card -- for Campbell Biology in Focus (2nd Edition)
Ch. 35.1 - Pus is both a sign of infection and an indicator...Ch. 35.1 - MAKE CONNECTIONS How do the molecules that...Ch. 35.1 - Prob. 3CCCh. 35.2 - Prob. 1CCCh. 35.2 - Explain how memory cells strengthen the immune...Ch. 35.2 - WHAT IF? If both copies of a light-chain gene and...Ch. 35.3 - Prob. 1CCCh. 35.3 - Prob. 2CCCh. 35.3 - Prob. 3CCCh. 35 - Prob. 1TYU
Ch. 35 - Prob. 2TYUCh. 35 - Prob. 3TYUCh. 35 - Prob. 4TYUCh. 35 - Prob. 5TYUCh. 35 - Prob. 6TYUCh. 35 - Prob. 7TYUCh. 35 - DRAW IT Consider a pencil-shaped protein with two...Ch. 35 - MAKE CONNECTIONS Contrast clonal selection with...Ch. 35 - Prob. 10TYUCh. 35 - FOCUS ON EVOLUTION Describe one invertebrate...Ch. 35 - Prob. 12TYUCh. 35 - Prob. 13TYU
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