BIOCHEM-ACHIEVE(FIRST DAY DISCOUNTED)
9th Edition
ISBN: 2818000069358
Author: BERG
Publisher: MAC HIGHER
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Question
Chapter 35, Problem 20P
Interpretation Introduction
Interpretation:
A protein having an immunoglobulin domain will have a function in the immune system, if this statement is correct or not should be determined.
Concept introduction:
The immunoglobulin superfamily is a protein superfamily having cell surface and soluble proteins. They all have the structure that resembles the structure of the immunoglobulins or the antibodies.
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You are an energetic immunology student who has isolated protein X, which you believe is a new isotype of human immunoglobulin. What structural features would protein X have to have to be classified as an immunoglobulin? Make diagram to illustrate your answer.
An antigen acts is a molecule that acts like a name tag, allowing
the immune system to recognize the cell it is attached to. The
name tag might say: "Hello I'm... a deadly virus," or “Hello
I'm... a healthy human cell." It is very important that an
antigen for a deadly virus and a healthy human cell are very
different, so that the immune system does not make a mistake
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Which of the following molecules do you think would make
good antigens for recognizing a pathogen? Justify your
answer.
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1) a cell wall protein
2) a piece of DNA inside a cell
3) a protein that is part of a flagella
4) a uniquely shaped protein that is part of a virus
5) a protein that is only made by prokaryotic cells
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Like many proteins that do their jobs outside of cells, immunoglobulin G is a glycoprotein. The oligosaccharide chains are attached to the “stem” of the Y-shaped molecule and are believed to help protect the protein. Based on your understanding of carbohydrates, explain why it would not make sense for the immunoglobulin’s two antigen-binding arms to have attached oligosaccharides
Chapter 35 Solutions
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