Biochemistry
8th Edition
ISBN: 9781464126109
Author: Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr., Lubert Stryer
Publisher: W. H. Freeman
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Chapter 36, Problem 5P
Interpretation Introduction
Interpretation:
The difference between the phase I and phase II clinical trials in relation to the number of enrolled persons, state of health of the subjects and goals of the study should be determined.
Concept introduction:
Clinical trials are the research investigations that involve volunteer people to test new treatments. Also, it involves the interventions or tests as a means to avoid, distinguish, treat or manage several diseases or medical situations.
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A clinical trial was carried out to test whether a new treatment affects the recovery rate of patients suffering from a debilitating disease. The null hypothesis “H0: The treatment has no effect” was rejected with a P-value of 0.04. The researchers used a significance level of a = 0.05. State whether each of the following conclusions is correct. If not, explain why:
a)The treatment has only a small effect ()
b)The treatment has some effect ()
c)The probability of committing a Type I error is 0.04 ()
d)The probability of committing a Type II error is 0.04 ()
e)The null hypothesis would not have been rejected had the significance level been set to a = 0.01 instead of 0.05. ()
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