Interpretation:
The configuration of the given structure of Tamiflu has to be given.
Concept introduction:
Asymmetric center is a stereocenter which arises to a compound if any atom is bonded to four different groups.
According to Cahn-Ingold-Prelog system,
The group attached to asymmetric center should be ranked based on the
Check the direction of arrow drawn in the direction of decreasing priority. If the arrow points clockwise direction, then the compound has R configuration. If the arrow points counterclockwise direction, then the compound has S configuration. If the group with lowest priority is not bonded by a hatched wedge, then interchange this group (lowest priority) by group bonded to hatched wedge and draw the arrow in priority order but the configuration is assigned as just reverse.
Want to see the full answer?
Check out a sample textbook solutionChapter 4 Solutions
ORGANIC CHEMISTRY (LOOSELEAF)-PACKAGE
- A mixture of equal amounts of two enantiomers... a) is optically inactive (does not rotate the beam of plane-polarized light) b) is called a racemic mixture c) is a meso compound d) both a and barrow_forwardAssign an R or S configuration to each chiral centerarrow_forward(Part 2 says Diastereomers or Enantiomers)arrow_forward
- The figure can rotate the plane of polarized light by 4.52 counterclockwise, 1. what is its configuration based on optical activity, 2. what is the absolute and relative configuration of the figure and 3. what is the angle of rotation of the plane-polarized light of its ENANTIOMERarrow_forwardSome sugar substitutes are made from derivatives of sucrose. Sucralose™ is a sweetener found in soft drinks and low-calorie foods such as yogurt. The structure of Sucralose is shown in both 2D and 3D representations. How many chirality centers are present?arrow_forwardWhat is the configuration of the two chirality centers?arrow_forward
- What are diastereomers? a. Constitutional isomers. b. Molecules with only one chiral center. c. Stereoisomers that are not mirror images of one another and are non-superimposable on one another. d. Stereoisomers that are mirror images of one another.arrow_forwardDoes lactic acid have enantiomers or stereoisomers?And explain why ...arrow_forwardMolnupiraviris a promising drug candidate that is discovered to treat patients with Covid-19. The drug is more advantageous than Remdesivir because it is administered orally. The structure of Molnupiraviris drawn below: *Figure in the screenshot* a. How many chirality centers exist on this drug? b. How many maximum numbers of stereoisomers with respect to chiral centers exist? c. Determine R/S configuration of each chiral centeronMolnupiravirby pointing to each chiral center with an arrow on the structure above d. Draw the enantiomer of Molnupiraviracross from it above e. MolnupiravirdestroysCorona virus by introducing error during viral RNA replication. If you were a physician, would you administer a pill that consists of a racemic mixture of Molnupiravirand its enantiomer to a covid positive patient? What would be your expectations? Give your reasons.arrow_forward
- Introduction to General, Organic and BiochemistryChemistryISBN:9781285869759Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar TorresPublisher:Cengage LearningOrganic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning