Concept explainers
Interpretation:
For the four isomeric
Concept introduction:
The absolute configuration is the three dimensional spatial arrangement of substituents at the chiral center.
The R and S configuration at the chiral center is assigned on the basis of Cahn-Ingold-Prelog rules.
The molecule is oriented such that the lowest ranked group points away from the observer.
If the remaining three groups in order of decreasing priority trace a clockwise path, the configuration is R.
If the remaining three groups in order of decreasing priority trace a counter clockwise path, the configuration is S.
In Fischer projections, the molecule is oriented such that the vertical bonds attached to the chiral center are directed away from the observer and the horizontal bonds point towards the observer.
When two groups are exchanged in a Fischer projection, it reverses the configuration of the chiral center.
Enantiomers are the mirror images of each other; they have opposite configuration at the each chirality center.
Diastereomers have at least two chiral centers and they are not mirror images of each other; they must have an opposite configuration for at least one chirality centers.
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ORGANIC CHEM BUNDLE >BI<
- Does the following compound have the R or the S configuration?arrow_forwardWhy are the last two compounds called meso diastereomers? I understand the meso part, but aren't diastereomers compounds that are neither mirror images or superimposable? It's clear the two Fischer projections are mirror images to me.arrow_forwardIn a fischer projection, is the molecule r or s, and what is the highest priority?arrow_forward
- Draw (2S, 3R)-2-bromo-3-chloropentane on the Fischer projection shown below.arrow_forwardWrite the configuration of two chirality centers in 4-chloro-2,3-dimethyl-3-pentanol presented through Fischer projection below in a form of short answer: (3R,4R); (3S,4S); (3R,4S); or (3S,4R).arrow_forwardIs my answer to this fischer projection conversion correct?arrow_forward
- 11. Identify the correct configurations (R or S) of the chirality centers indicated on the Fischer projection shown below.arrow_forwardIs my answer correct? Is it okay to put the hydrogen in the back for the fourth carbon despite it being in the front in the Fischer projection?arrow_forwardMake sure to answer the quesi to chem below Using the priority rule, identify the configuration at each chiral center and the configuration of the double bond: For a chiral center please type EXACTLY one of the following: R or S or neither if it is not a chiral center. For a double bond please type EXACTLY one of the following: E or Z or neither if the double bond has no stereochemistry.arrow_forward
- Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning