CUSTOM BIOLOGY
19th Edition
ISBN: 9781323945490
Author: Urry
Publisher: Pearson Custom Publishing
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Question
Chapter 41.5, Problem 3CC
Summary Introduction
To explain: The effect of insulinomas on blood glucose levels and liver functions.
Introduction:
Insulinomas are cancerous insulin-producing beta cells of pancreatic islets of Langerhans. These tumors lack response to feedback mechanisms and secret insulin even when there is a low blood glucose level in the body.
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82. Regulation of cellular metabolism by insulin requires activation of the insulin-receptor substrate protein-1 (IRS1). Some individuals who have type 2 diabetes mellitus have mutations in the
IRS1 gene. Which of the following normal steps in insulin signaling is most likely to be impaired by these mutations?
A) Cleavage of IRS1 by the insulin receptor
B) Phosphorylation of IRS1 by the insulin receptor
C) Production of inositol 1,4,5-trisphosphate by IRS1
D) Stimulation of a G protein by IRS1
E) Synthesis of diacylglycerol by IRS1
Match the molecule involved in insulin signaling with what it does
insulin receptor
[Choose ]
[Choose]
physically pushes glucose out of the cell
physically brings glucose into the cell
binds to insulin and sends signal to cell
a protein hormone that signals cells to import glucose
signals cells to export glucose
a carbohydrate taken into cells as an energy source
glucose
insulin
glucose transporter
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近
. What would be the effect of a mutation in the gene for PTP1B (protein tyrosine phosphatase 1B) that inactivated the enzyme in a person who has type 2 diabetes?
Chapter 41 Solutions
CUSTOM BIOLOGY
Ch. 41.1 - An animal requires 20 amino acids to make...Ch. 41.1 - Prob. 2CCCh. 41.1 - WHAT IF? If a zoo animal eating ample food shows...Ch. 41.2 - Prob. 1CCCh. 41.2 - In what sense are nutrients from a recently...Ch. 41.2 - Prob. 3CCCh. 41.3 - Explain why a proton pump inhibitor, such as the...Ch. 41.3 - Prob. 2CCCh. 41.3 - Prob. 3CCCh. 41.4 - Prob. 1CC
Ch. 41.4 - What features of a mammal's digestive system make...Ch. 41.4 - WHAT IF? "Lactose-intolerant" people have a...Ch. 41.5 - Explain how people can become obese even if their...Ch. 41.5 - WHAT IF? Suppose you were studying two groups of...Ch. 41.5 - Prob. 3CCCh. 41 - Prob. 41.1CRCh. 41 - Propose an artificial diet that would eliminate...Ch. 41 - Prob. 41.3CRCh. 41 - How does human anatomy indicate that our primate...Ch. 41 - Prob. 41.5CRCh. 41 - Fat digestion yields fatty acids and glycerol....Ch. 41 - The mammalian trachea and esophagus both connect...Ch. 41 - Prob. 3TYUCh. 41 - Prob. 4TYUCh. 41 - Prob. 5TYUCh. 41 - After surgical removal of the gallbladder, a...Ch. 41 - If you were to jog 1 km a few hours after lunch,...Ch. 41 - DRAW IT Create a flowchart to summarize the events...Ch. 41 - EVOLUTION CONNECTION Lizards and snakes cannot...Ch. 41 - SCIENTIFIC INQUIRY In human populations of...Ch. 41 - WRITE ABOUT A THEME: ORGANIZATION Hair is largely...Ch. 41 - SYNTHESIZE YOUR KNOWLEDGE Hummingbirds are well...
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