MODIFIED MASTERING BIOLOGY WITH PEARSO
11th Edition
ISBN: 9780134447292
Author: Urry
Publisher: PEARSON EDUCATION (COLLEGE)
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Question
Chapter 43.2, Problem 1CC
Summary Introduction
To draw: The structure of B-cell antigen and features located relative to V and C regions
Concept introduction:
The structure of a B cell resembles the “Y” shape. It consists of four polypeptide chains that include two identical heavy chains and, two identical light chains.
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DRAW IT Sketch a B cell antigen receptor. Label the Vand C regions of the light and heavy chains. Label theantigen-binding sites, disulfide bridges, and transmembrane region. Where are these features located relativeto the V and C regions?
Consider a pencil-shaped protein with two epitopes, Y (the “eraser” end) and Z (the “point” end). They are recognized by antibodies A1 and A2, respectively. Draw and label a picture showing the antibodies linking proteins into a complex that could trigger endocytosis by a macrophage.
Sketch a B cell antigen receptor. Label the V and C regions of the light and heavy chains. Label the antigenbinding sites, disulfide bridges, and transmembrane region. Where are these features located relative to the V and C regions?
Chapter 43 Solutions
MODIFIED MASTERING BIOLOGY WITH PEARSO
Ch. 43.1 - Pus is both a sign of infection and an indicator...Ch. 43.1 - MAKE CONNECTIONS How do the molecules that...Ch. 43.1 - Prob. 3CCCh. 43.2 - Prob. 1CCCh. 43.2 - Prob. 2CCCh. 43.2 - WHAT IF? If both copies of a light-chain gene and...Ch. 43.3 - Prob. 1CCCh. 43.3 - Treatment of antibodies with a particular protease...Ch. 43.3 - Prob. 3CCCh. 43.4 - Prob. 1CC
Ch. 43.4 - Prob. 2CCCh. 43.4 - WHAT IF? How would a macrophage deficiency likely...Ch. 43 - In what ways does innate immunity protect the...Ch. 43 - Why is the adaptive immune response to an initial...Ch. 43 - Is immunological memory after a natural infection...Ch. 43 - Prob. 43.4CRCh. 43 - Prob. 1TYUCh. 43 - An epitope associates with which part of an...Ch. 43 - Prob. 3TYUCh. 43 - Level 2: Application/Analysis 4. Which of the...Ch. 43 - Prob. 5TYUCh. 43 - Prob. 6TYUCh. 43 - Prob. 7TYUCh. 43 - Prob. 8TYUCh. 43 - MAKE CONNECTIONS Contrast clonal selection with...Ch. 43 - EVOLUTION CONNECTION Describe one invertebrate...Ch. 43 - Prob. 11TYUCh. 43 - Prob. 12TYUCh. 43 - SYNTHESIZE YOUR KNOWLEDGE This photo shows a child...
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- Which of the following is not a part of innate immunity? a. phagocytic cells e. inflammation b. fever f. complement activation c. histamines g. presenting antigen d. cytokines h. all take partarrow_forwardMatch the immune cell with its main function. ___dendritic cell a. professional phagocyte ___B cell b. antigen-presenter ___helper T cell c. activates other lymphocytes ___NK cell d. makes antibodies ___macrophage e. kills ailing body cells that lack MHC markersarrow_forwardAntibodies are_________. a. antigen receptors b. made only by B cells c. proteins d. all of the abovearrow_forward
- Activated complement proteins ________. a. puncture cells c. attract macrophages b. promote inflammation d. all of the abovearrow_forwardMatch the immunity concept with the best description. ___anaphylactic shock a. recognizes antigen ___immune memory b. inadequate immune response ___autoimmunity c general defense mechanism ___inflammation d. immune response against ones own body ___immune deficiency e. secondary response ___antigen receptor f. acute allergic reaction ___antigen processing g. presenting antigen together with MHC markersarrow_forwardMatch the immunity concept with the best description. _____ anaphylactic shock a. recognizes antigen _____ immune memory b. insufficient immune response _____ immune deficiency c. general defense mechanism _____ autoimmunity d. immune response against ones own body _____ antigen receptor e. secondary response _____ inflammation f. acute allergic reactionarrow_forward
- i. Draw a schematic diagram of a typical IgG molecule and label each of the following parts: H chains, L chains, intrachain disulfide bonds, hinge, Fab, Fc, and all the domains. Indicate which domains are involved in antigen binding.arrow_forward1.A given B cell expresses only maternally or paternally derived heavy chains but never both. This observation is the result of A. antibodydiversity.B. isotypeswitching.C. allelicexclusion.D. affinitymaturation.E. randomVJgenerearrangement. 2.Which of the following antibody classes or isotypes facilitate the sequential binding of the C1, C4, C2, and C3 components of the complement system? A. IgAandIgD B. IgAandIgE C. IgDandIgM D. IgE and IgG E. IgMandIgGarrow_forwardWhich statement is incorrect?a. IgG is the most abundant antibody in bloodb. Antibodies can exist at the surface of a B cell, or circulate freely in blood.c. IgM is found in the lining of the genitourinary, gastrointestinal and respiratory tractsd. IgE is involved allergic reactionse. Macrophages are involved in chronic infectionsarrow_forward
- Match the terms to their most approriate description. Select the INCORRECT match. a. Subunit vaccine / Part of a pathogen rather than the complete cell or virus b. Toxoid / Antigenic but non-toxic derivative of a toxin c. Perforin / Molecule that is part of the complement cascade d. Antitoxin / Neutralizing antibodies e. Superantigen / Bacterial exotoxin that activates a high percentage of T cellsarrow_forwardA. In table form, differentiate Primary from Secondary Immune Response according to the ff. a. type of Ig b. action of memory cells c. amount and speed of antibody production d. recognition phase e. timing of exposure B. In table form, differentiate Cell mediated from Antibody mediated (humoral) Immunity according to type of cells involved and product form C. Enumerate 5 lab tests/procedures done to obtain/identify Lymphocytes. Then briefly discuss one.arrow_forwardAbout Antigen presenting cells, it is CORRECT to affirm that: a). Macrophages, B lymphocytes and dendritic cells are APCs. meaning they express MHC-ll. b). Only APCs present MHC-11. c). Macrophages,B lymphocytes and dendritic cells are phagocytes, but not APCs.d). All the non-APC cells of our body present MHC-1.arrow_forward
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