Lycopene, which is abundant in tomatoes, is thought to have a potential benefit in protecting against many types of cancers. In the study, the results of which are shown in the Figure, mice were exposed to tobacco smoke or normal air. The amount of lung tissue damage caused by each exposure was measured in mice that were given tomato juice (1) or water (2). To estimate the destruction of the alveolar wall, a destructive index (DI) was calculated from histological slides of the lung. All lungs will show some level of damage, but a DI above 10% is considered significant destruction.
What is the effect of tobacco smoke on the lung tissue in these mice?
Source: Based on S. Kasagi et al. 2006. Tomato juice prevents senescence-accelerated mouse P1 strain from developing emphysema induced by chronic exposure to tobacco smoke. American Journal of Physiology–Lung Cellular and Molecular Physiology 290:L396–L404.
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Biology: The Dynamic Science (MindTap Course List)
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