CAMPBELL BIOLOGY,VOL.II >CUSTOM<
CAMPBELL BIOLOGY,VOL.II >CUSTOM<
17th Edition
ISBN: 9781323803677
Author: Urry
Publisher: PEARSON
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Chapter 47, Problem 47.3CR

Suppose you found two classes of mouse mutations, one that .affected limb development only and one that affected both limb and kidney development. Which class would be more likely to alter the function of monocilia? Explain.

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Suppose you found two classes of mouse mutations, one that affectedlimb development only and one that affected both limb and kidneydevelopment. Which class would be more likely to alter the functionof monocilia? Explain.
You are studying a mutation in mice, which acts dominantly. Mice that have only one copy of the allele carrying this mutation have a kinky tail phenotype. You identify the gene that the mutation affects and find that the codon that encodes the second amino acid in the predicted protein has been mutated to a stop codon. Would you characterize this mutation as a loss-of-function or a gain-of-function and what specific subtype (hypermorphic, antimorphic, etc. ) within these categories? Explain your reasoning.”
given a situation in which you manipulated a zebrafish embryo by injecting high levels of retinoic acid so that no anterior genes will be expressed. Surprisingly, after embryonic development, you are still able to observed the presence of anterior structures. What could explain this observation? What changes in your experiment would you make to achieve your objective?
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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY