Concept explainers
(a)
Interpretation: The stereogenic center in the given molecule must be assigned R or S configuration.
Concept introduction: Stereogenic centres are given R and S configuration by sequence rule that is by assigning 1 to 4 priorities to the substituents attached at the chiral center on the basis of their
(b)
Interpretation: The stereogenic center in the given molecule must be assigned R or S configuration.
Concept introduction: Stereogenic centres are given R and S configuration by sequence rule that is by assigning 1 to 4 priorities to the substituents attached at the chiral center on the basis of their atomic number higher the atomic number higher is the priority followed by rotating the molecule from the side of highest priority group to that of the lowest priority. If the molecule rotates in clockwise direction then it is assigned R configuration while if it rotates in anticlockwise direction then it is assigned S configuration. If the first priority atom of the substituent groups is same then the priority of second atom is checked and so on.
(c)
Interpretation: The stereogenic center in the given molecule must be assigned R or S configuration.
Concept introduction: Stereogenic centres are given R and S configuration by sequence rule that is by assigning 1 to 4 priorities to the substituents attached at the chiral center on the basis of their atomic number higher the atomic number higher is the priority followed by rotating the molecule from the side of highest priority group to that of the lowest priority. If the molecule rotates in clockwise direction then it is assigned R configuration while if it rotates in anticlockwise direction then it is assigned S configuration. If the first priority atom of the substituent groups is same then the priority of second atom is checked and so on.
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Organic Chemistry -Study Guide / Solution Manual (Custom)
- Locate the stereogenic centers in each drug. Albuterol is a bronchodilator—that is, it widens airways—so it is used to treat asthma. Chloramphenicol isan antibiotic used extensively in developing countries because of its lowcost.arrow_forwardLocate the stereogenic centers in attached compound. A molecule may have one or more stereogenic centers. Gabapentin enacarbil [part (d)] is used to treat seizures and certain types of chronic pain.arrow_forwardThe structure of 4 isomers of ketopentose are shown. 1) select every structure that is a diastereomer of structure D A, B, or C? 2) select every structure that is a enantiomer of structure C A, B, or D 3) select every structure that is a stereoisomer of structure C A, B, or Darrow_forward
- Locate the stereogenic centers in each compound. A molecule may have one or more stereogenic centers. Gabapentin enacarbil [part (d)] is used to treat seizures and certain types of chronic pain.arrow_forwardLabel attached stereogenic center as R or S.arrow_forwardLabel each stereogenic center in the following compounds as R or S.arrow_forward
- Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning