Biology
Biology
12th Edition
ISBN: 9781260494570
Author: Raven, Peter
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 51, Problem 3S

How are the functions of FSH and LH similar in male and female mammals? How do they differ?

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10. Researchers have discovered a new compound that is a candidate for birth control. Its proposed mechanism is to be a progesterone receptor agonist meaning that it binds and activates receptors that would normally recognize progesterone. Researchers are interested in understanding the efficacy of the new compound, in other words, how well does its progesterone receptor agonist activity prevent the possibility of pregnancy. Assume that we are working in a rodent model system (mouse or rat) and propose a research design to test the efficacy of this compound. This design needs to address the proposed mechanism that this compound is a progesterone receptor agonist. Include a description of the variables in the experiment, the treatment groups, the procedure to detect the efficacy of the proposed mechanism, and an explanation of the results that would be required to confirm the efficacy of this compound for birth control. D. Focus 五
2. List (just list) two similarities and two differences between luteinizing hormone (LH) and human chorionic gonadotropin (hCG). You can consider such aspects as where they are produced, their structures, their functions, etc. From an evolutionary perspective, why do you think they are so similar to each other?
14. Testosterone is a hormone produced by male testes. The diagram below shows a negative feedback system controlling testosterone concentration. Hypothalamus GnRH [(+) Pituitary gland LH and FSH [(+) Testes (-) (--) Key (+) stimulates (-) inhibits Sperm cells GnRH - gonadotropin- releasing hormone LH-luteinising hormone FSH-follicle-stimulating hormone Testosterone J will reduce testosterone levels by inhibiting LH and FSH. K will reduce testosterone levels by stimulating GnRH secretion. L will increase testosterone levels by inhibiting LH and FSH. M Will increase testosterone levels by stimulating GnRH secretion
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