Biology
Biology
10th Edition
ISBN: 9780073383071
Author: Raven
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 51, Problem 4S

Toll-like receptors have been found in a wide variety of organisms, including both protostomes and deuterostomes, and now in cnidarians. In addition, parts of the signaling system have been found in a wide variety of organisms as have parts of the complement system. What does this say about the evolution of innate immunity?

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For some time there has been evidence that the Bacille Calmette-Guérin (BCG) vaccine provides protection not only against the target disease (Mycobacterium tuberculosis), but also enhances responses to other infections (such as Staphylococcus aureus and Candida albicans). Do you think the enhanced response to other infections, as described, is due to innate responses to the vaccine or adaptive responses? Explain your answer.
In Lubeck, Germany, in 1930, a group of 251 infants was accidentally administered a tainted vaccine for tuberculosis that contained live Mycobacterium tuberculosis. This vaccine was administered orally, directly exposing the infants to the deadly bacterium. Many of these infants contracted tuberculosis, and some died. However, 44 of the infants never contracted tuberculosis. Based on your knowledge of the innate immune system, what innate defenses might have inhibited M. tuberculosis enough to prevent these infants from contracting the disease?
Sponges display nonspecific immunity. In an experiment, the cells of two different sponges were mixed and placed within a petri dish. The cells from each sponge sorted and arranged themselves together according to organism. What does this characteristic demonstrate?   A. Sponges have memory T-cells and share a more recent common ancestor with vertebrates than other invertebrates. B. The experiment provides evidence for the speed of evolution and the use of specific immunity within the organism. C. Sponges have an ability to recognize their own cells as a characteristic of acquired immunity. D. Sharing genetic information from cell to cell is possible by means of receptors and protein-lined pits.
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