Gen Combo Ll Biology; Connect W/learnsmart Labs Access Card
4th Edition
ISBN: 9781259853197
Author: Robert Brooker
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Question
Chapter 5.3, Problem 2CC
Summary Introduction
To explain: The structural feature of a polypeptide that causes a region to form transmemrane segment.
Introduction: The proteins are found in two different forms in the cell membrane. The first forms are embedded in the membrane and hence are called transmembrane proteins or integrin proteins. The other types of proteins are found at the periphery of the cell membrane and are called as peripheral proteins. These both proteins are made up of the polypeptide chains but it is the two dimensional structure that decides their role.
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a) (i) Give THREE (3) amino acids that most likely can be located in the
part of the trans- membrane protein that lies within the cell
membrane. Explain why.
(ii)Give THREE (3) amino acids that most likely can be
located in the part of the transmembrane protein that lies outside
the cell membrane. Explain why.
Four of the most abundant amino acids in proteins are leucine, alanine, glycine, and valine. What do these amino acids have in common? Would you expect these amino acids to be found on the interior or on the exterior of theprotein?
What are the functions of thesurprisingly large amount of unfoldedpolypeptide chain found in proteins?
Chapter 5 Solutions
Gen Combo Ll Biology; Connect W/learnsmart Labs Access Card
Ch. 5.1 - Prob. 1CCCh. 5.2 - Prob. 1CCCh. 5.2 - Prob. 2CCCh. 5.2 - Prob. 1BCCh. 5.3 - Prob. 1CCCh. 5.3 - Prob. 2CCCh. 5.4 - Prob. 1BCCh. 5.4 - Which molecule would you expect to pass through a...Ch. 5.4 - Prob. 2BCCh. 5.4 - Lets suppose the inside of a cell has a solute...
Ch. 5.5 - What is the purpose of gating?Ch. 5.5 - Prob. 1EQCh. 5.5 - Prob. 2EQCh. 5.5 - Prob. 3EQCh. 5.5 - Prob. 2CCCh. 5.6 - What is the function of the protein coat?Ch. 5 - Prob. 1TYCh. 5 - Which of the following events can never be...Ch. 5 - Lets suppose an insect, which doesnt maintain a...Ch. 5 - Prob. 4TYCh. 5 - Prob. 5TYCh. 5 - Prob. 6TYCh. 5 - Prob. 7TYCh. 5 - Prob. 8TYCh. 5 - Prob. 9TYCh. 5 - Large particles or large volumes of fluid can be...Ch. 5 - With your textbook closed, draw and describe the...Ch. 5 - Prob. 2CQCh. 5 - Prob. 3CQCh. 5 - Prob. 1COQCh. 5 - With regard to bringing solutes into the cell...
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- What exactly causes the P, A, and E sites in ribosomes to form and when do they form?arrow_forwardIs adenylate cyclase a transmembrane protein or a peripheralprotein? What about the G protein?arrow_forwardDisulfide linkages are uncommon in cytoplasmic proteins, whereas they are common in extracellular proteins. Why?arrow_forward
- Which amino acids would you expect to find buried in the interior of peripheral membrane protein ?arrow_forwardThe usual hydrophobic region of a membrane is around 30 Angstroms. Knowing this, about many amino acid residues would a transmembrane helix have?arrow_forwardExplain why the polypeptide chain of most transmembrane proteins crosses the lipid bilayer as an α helix or a β barrel.arrow_forward
- Polypeptides which are normally synthesized in the endoplasmic reticulum are about20 amino acids longer when they are synthesized by ribosomes not attached to the endoplasmicreticulum, What is the significance of this increase in length?arrow_forwardHow does a polypeptide fold to become a functioning protein?arrow_forwardwhat are three proteins that are abundantly present in ECM( Extracellular matrix)?arrow_forward
- B) We also know from studies of protein structure that one turn of an a-helix includes 3.6 amino acid residues and extends the long axis of the helix by - 0.56 nm. Approximately how many amino acids must a helical transmembrane segment of an integral membrane protein have if the segment is to span the lipid bilayer defined by two stearate molecules laid end to end, plus the polar head groups to which the stearate molecules are attached (assume a polar head group has a diameter of 0.5 nm)?arrow_forwardMicrofilaments are long filamentous proteins made up of many globular proteins. What main protein are microfilaments composed of?arrow_forwardHow does the process of protein synthesis differ in Prokaryotes and Eukaryotes? Discuss factors other than ribosome size.arrow_forward
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