Human Physiology: An Integrated Approach (8th Edition)
8th Edition
ISBN: 9780134605197
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Chapter 5.4, Problem 24CC
Summary Introduction
To determine: The two ways in which Na+-K+-ATPase is different from SGLT.
Introduction: Active transport can be divided into two types: primary active transport and secondary active transport. Sodium-glucose secondary active transporter (SGLT) is an example of secondary active transport.
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Chapter 5 Solutions
Human Physiology: An Integrated Approach (8th Edition)
Ch. 5.1 - If the 58-kg Reference Woman has total body water...Ch. 5.1 - A mother brings her baby to the emergency room...Ch. 5.1 - Prob. 6CCCh. 5.1 - Two compartments are separated by a membrane that...Ch. 5.1 - Prob. 8CCCh. 5.1 - Prob. 9CCCh. 5.1 - Prob. 10CCCh. 5.3 - If the distance over which a molecule must diffuse...Ch. 5.3 - Prob. 12CCCh. 5.3 - Which is more likely to cross a cell membrane by...
Ch. 5.3 - Prob. 14CCCh. 5.3 - Prob. 15CCCh. 5.3 - Prob. 16CCCh. 5.4 - Positively charged ions are called _____, and...Ch. 5.4 - Name four functions of membrane proteins.Ch. 5.4 - Prob. 19CCCh. 5.4 - Prob. 20CCCh. 5.4 - If a channel is lined with amino acids that have a...Ch. 5.4 - Prob. 22CCCh. 5.4 - Liver cells (hepatocytes) are able to convert...Ch. 5.4 - Prob. 24CCCh. 5.5 - What would you call a carrier that moves two...Ch. 5.5 - Prob. 26CCCh. 5.5 - Prob. 27CCCh. 5.5 - Name the two membrane protein families associated...Ch. 5.5 - Prob. 29CCCh. 5.6 - Prob. 30CCCh. 5.6 - Prob. 31CCCh. 5.6 - Prob. 32CCCh. 5.6 - Prob. 33CCCh. 5.7 - Prob. 34CCCh. 5 - Using what you learned about the naming...Ch. 5 - Prob. 2CCCh. 5 - Prob. 3CCCh. 5 - Prob. 1RQCh. 5 - Distinguish between active transport and passive...Ch. 5 - Which of the following processes are examples of...Ch. 5 - List four factors that increase the rate of...Ch. 5 - List the three physical methods by which materials...Ch. 5 - A cotransporter is a protein that moves more than...Ch. 5 - Prob. 7RQCh. 5 - Prob. 8RQCh. 5 - Prob. 9RQCh. 5 - What determines the osmolarity of a solution? In...Ch. 5 - Prob. 11RQCh. 5 - Prob. 12RQCh. 5 - Prob. 13RQCh. 5 - Prob. 14RQCh. 5 - The membrane potential at which the electrical...Ch. 5 - Prob. 16RQCh. 5 - Create a map of transport across cell membranes...Ch. 5 - Draw a large rectangle to represent the total body...Ch. 5 - What factors influence the rate of diffusion...Ch. 5 - Define the following terms and explain how they...Ch. 5 - Prob. 21RQCh. 5 - Prob. 22RQCh. 5 - Prob. 23RQCh. 5 - Prob. 24RQCh. 5 - Prob. 25RQCh. 5 - Prob. 26RQCh. 5 - The following terms have been applied to membrane...Ch. 5 - Prob. 28RQCh. 5 - NaCl is a nonpenetrating solute and urea is a...Ch. 5 - Prob. 30RQCh. 5 - Prob. 31RQCh. 5 - What is the osmolarity of half-normal saline (=...Ch. 5 - Prob. 33RQCh. 5 - Prob. 34RQ
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- Which statements are true? Explain why or why not.1 Transport by transporters can be either active orpassive, whereas transport by channels is always passive.2 Transporters saturate at high concentrations ofthe transported molecule when all their binding sites areoccupied; channels, on the other hand, do not bind theions they transport and thus the flux of ions through achannel does not saturate.3 The membrane potential arises from movementsof charge that leave ion concentrations practically unaf-fected, causing only a very slight discrepancy in the num-ber of positive and negative ions on the two sides of themembrane.arrow_forwardName the three classes of membrane transport proteins. Explain which one or ones of these classes is able to move glucose and which can move bicarbonate (HCO3 −) against an electrochemical gradient. In the case of bicarbonate, but not glucose, the ΔG of the transport process has two terms.What are these two terms, and why does the second not apply to glucose? Why are cotransporters often referred to as examples of secondary active transport?arrow_forwardName the three classes of membrane transport proteins. Explain which one or ones of these classes is able to move glucose and which can move bicarbonate (HCO3−) against an electrochemical gradient. In the case of bicarbonate, but not glucose, the ΔG of the transport process has two terms. What are these two terms, and why does the second not apply to glucose? Why are cotransporters often referred to as examples of secondary active transport?arrow_forward
- Below find the structures for ibogaine and cocaine. Ibogaine and cocaine inhibit the dopamine active transporter (DAT). This transporter is a secondary active transporter, and depends on the primary active transporter Na+/K+ ATPase. Ibogaine had a Kι = 2 μM, and cocaine a Kι = 0.64 μM respectively. (a) Define secondary active transport. (b) Is ibogaine an effective treatment for cocaine based on DAT binding?arrow_forwardCompare and contrast simple transporters, thephosphotransferase system, and ABC transporters in terms of(1) energy source, (2) chemical alterations of the solute duringtransport, and (3) number of proteins requiredarrow_forwardWhat might determine the value for the maximal flux of a mediated transport?arrow_forward
- Name the Na channel locus, formed by amino acid residues, that determines specificity of the channel. a. P-type ATPase O b. ABC transporter O C. DEKA O d. MDR O e. SERCAarrow_forwardWhat is a secondary transporter? Why are they called secondary? What is [3 H]Leu? Explain both 3H and Leu.arrow_forwardIn the situations described below, what is the free energy change if 1 mole of Na+ is transported across a membrane from a region where the concentration is 48 μM to a region where it is 110 mM? (Assume T=37∘C.) When the transport is opposed by a membrane potential of 70 mV.arrow_forward
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