Chapter 6, Problem 10P

1.

Summary Introduction

To determine: The deleterious effect of the mutational change including insertion of a single nucleotide near the end of the coding sequence to the gene function.

Introduction: All cells in the body contain DNA so, there are many places for mutational changes. Some are silent mutations but when a mutation affects a protein, it can disrupt normal functioning of the body.

2.

Summary Introduction

To determine: The deleterious effect of the mutational change including removal of a single nucleotide near the beginning of the coding sequence to the gene function.

Introduction: All cells in the body contain DNA so, there are many places for mutational changes. Some are silent mutations but when a mutation affects a protein, it can disrupt normal functioning of the body.

3.

Summary Introduction

To determine: The deleterious effect of the mutational change including deletion of three consecutive nucleotides in the middle of the coding sequence to the gene function.

Introduction: All cells in the body contain DNA so, there are many places for mutational changes. Some are silent mutations but when a mutation affects a protein, it can disrupt normal functioning of the body.

4.

Summary Introduction

To determine: The deleterious effect of the mutational change including substitution of one nucleotide for another in the middle of the coding sequence.

Introduction: All cells in the body contain DNA so, there are many places for mutational changes. Some are silent mutations but when a mutation affects a protein, it can disrupt normal functioning of the body.