EBK BIOLOGY
EBK BIOLOGY
11th Edition
ISBN: 8220106820636
Author: Martin
Publisher: CENGAGE L
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Chapter 6, Problem 1TYU

During signal transduction (a) the cell converts an extracellular signal into an intracellular signal that leads to a change in some cell process (b) a signaling molecule directly activates or represses several genes (c) each enzyme catalyzes production of one molecule of product (d) enzymes in the signal cascade remain active until the last component of the pathway alters a cellular process (e) the signal is terminated by cyclic AMP

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Summary Introduction

Introduction: There are four sequences of events that take place in cell signaling. These are signal transmission, reception, signal transduction, and response. In signal transduction, the cell changes the extracellular signals into intracellular signals. Cell generates a number of internal molecules that work in a specific manner.

Answer to Problem 1TYU

Correct answer: Signal transduction is a process in which extracellular signals get converted into intracellular signals. Hence the correct answer is option (a).

Explanation of Solution

Reason for the correct answer:

Option (a) is given as “the cell converts an extracellular signal into an intracellular signal that leads to a change in some cell process”. In signal transduction, the cell changes the received extracellular signals into intracellular signals. Cell generates a number of internal molecules that work in a specific manner to cause a response. It may either activates genes or deactivate it.

Hence the correct answer is option (a).

Reasons for incorrect answers:

Option (b) is given as, “a signaling molecule directly activates or represses several genes”. A signaling molecule activates several downstream molecules which either activate or deactivates the genes. This is not part of signal transduction event. Hence, option (b) is incorrect.

Option (c) is given as, “each enzyme catalyzes production of one molecule of product”. The signal get amplified at each downstream of the pathway in which an enzyme catalyzes several other molecules. This is not part of signal transduction event. Hence, option (c) is incorrect.

Option (d) is given as, “enzymes in the signal cascade remain active until the last component of the pathway alters a cellular process”. Enzyme in the signal cascade gets inactivated once it activates the downstream molecules. It does not remain active until the last component for the pathway alters the process. This is not part of signal transduction event. Hence, option (d) is incorrect.

Option (e) is given as, “the signal is terminated by cyclic AMP”. Cyclic AMP is an effector molecule. It does not terminate the signal. The signal is terminated by phosphodiesterase which inactivates the cyclic AMP to AMP or phosphatase which inactivates the protein by removing phosphate group. This is not part of signal transduction event.

Hence, option (e) is incorrect.

Hence the options (b), (c), (d), and (e) are incorrect.

Conclusion

Signal transduction is a process in which extracellular signals get converted into intracellular signals which causes changes in cell processes.

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Cellular signaling follows a cascade of events and has multiple points of regulation. Which of the following could be a reason(s) why a signalling cascade is interrupted, or turned 'off', once it has been turned 'on'? A) a protein gets tagged with an ubiqutin group and gets degraded B) a chemical modification occurred on serine, threonine, or tyrosine side chains to turn on/off proteins C) allosteric regulation causes an active site to be hidden D) All of the other answers are correct E) The ligand is prevented from reaching the binding site
A small number of cell surface receptors and low amounts of signals (ligands) can generate a large intracellular response as each step of the signal transduction pathway can be expanded by... A. gene amplification, i.e. increasing the number of target genes. B.  enzyme-mediated signal amplification, e.g. phosphorylation cascades. C.  the synthesis of new proteins. D.  ATP Synthase, e.g. by building proton (H+) gradients.
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