Study Guide and Solutions Manual for Essentials of Genetics
9th Edition
ISBN: 9780134189987
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Harry Nickla
Publisher: PEARSON
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Textbook Question
Chapter 6, Problem 25PDQ
A 3-year-old child exhibited some early indication of Turner syndrome, which results from a 45, X chromosome composition. Karyotypic analysis demonstrated two cell types: 46, XX (normal) and 45, X. Propose a mechanism for the origin of this mosaicism.
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A chromosome of genotype C D recombines with a homolog of genotype c d during meiosis when Spo11 produces a double-strand break between genes C and D. If anticrossover helicase disentangles the invading strand, the likely outcome would be
A) two C D and two c d gametes. B) two C d and two c D gametes. C) one C D, one C d, one c D, and one c d gamete. D) four C D gametes. E) four c d gametes
Explain how mitotic recombination leads to the mosaiccondition termed twin spots.
An individual is heterozygous for a reciprocal translocation, with the following chromosomes:
A • B C D E F
A • B C V W X
R ST • U D E F
R ST • U V W X
Q. Draw the products of alternate, adjacent-1, and adjacent-2 segregations.
Chapter 6 Solutions
Study Guide and Solutions Manual for Essentials of Genetics
Ch. 6 - CASE STUDY| Fish tales Aquatic vegetation...Ch. 6 - CASE STUDY |Fish tales Aquatic vegetation...Ch. 6 - CASE STUDY |Fish tales
Aquatic vegetation...Ch. 6 - HOW DO WE KNOW? In this chapter, we focused on...Ch. 6 -
CONCEPT QUESTION
2. Review the Chapter Concepts...Ch. 6 -
3. Define these pairs of terms, and distinguish...Ch. 6 -
4. For a species with a diploid number of 18,...Ch. 6 - What explanation has been proposed to explain why...Ch. 6 - Contrast the fertility of an allotetraploid with...Ch. 6 -
7. Why do human monosomies most often fail to...
Ch. 6 -
8. Describe the origin of cultivated American...Ch. 6 - Predict how the synaptic configurations of...Ch. 6 - Inversions are said to “suppress crossing over.”...Ch. 6 -
11. Predict the genetic composition of gametes...Ch. 6 - Human adult hemoglobin is a tetramer containing...Ch. 6 -
13. The primrose, Primula kewensis, has 36...Ch. 6 - Certain varieties of chrysanthemums contain 18,...Ch. 6 - Drosophila may be monosomic for chromosome 4, yet...Ch. 6 - Mendelian ratios are modified in crosses involving...Ch. 6 -
17. Having correctly established the F2 ratio in...Ch. 6 -
18. In a cross between two varieties of corn,...Ch. 6 -
19. A couple planning their family are aware that...Ch. 6 -
20. A woman who sought genetic counseling is...Ch. 6 - The woman in Problem 20 has had two miscarriages....Ch. 6 -
22. In a recent cytogenetic study on 1021 cases...Ch. 6 -
23. A boy with Klinefelter syndrome (47,XXY) is...Ch. 6 - In a human genetic study, a family with five...Ch. 6 - A 3-year-old child exhibited some early indication...Ch. 6 - A normal female is discovered with 45 chromosomes,...
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- Genes R, H and F are located on the same chromosome. On one chromosome R, h and f alleles are attached, while on the homologue contains r, H and F. Which of the following would be an example of a recombination event?arrow_forwardWhat is mitotic recombination? A heterozygous individual (Bb)with brown eyes has one eye with a small patch of blue. Providetwo or more explanations for how the blue patch may have occurred?arrow_forwardTwo strains of S. cerevisae (yeast) are crossed. One has the genotype A B and the other a b. Which statement correctly describes the tetrads that can be produced by one reciprocal exchange between the A and B genes without gene conversion in the dihybrid? A) Recombination occurs at the four-strand stage to produce a tetrad with A B, A B, a B, and a b chromosomes. B) Recombination occurs at the four-strand stage to produce a tetrad with A B, A b, a B, and a b chromosomes. C) Recombination occurs at the two-strand stage to produce a tetrad with A B, A b, a B, and a b chromosomes. D) Recombination occurs at the two-strand stage to produce a tetrad with A b, A b, a B, and a B chromosomes.arrow_forward
- A colleague e-mails you saying that she has identified an interesting chromosome variation at 21q13. In discussing this discovery with a friend who is not a cytogeneticist, explain how you would describe this location, defining each term in the chromosome address 21q13.arrow_forwardVariations in Chromosome NumberAneuploidy Describe the process of nondisjunction and explain when it takes place during cell division.arrow_forwardAn individual heterozygous for a reciprocal translocation possesses the following chromosomes: A B • C D E F G A B • C D V W X R S • T U E F G R S • T U V W X Q. Give the products that result from alternate, adjacent-1, and adjacent-2 segregation.arrow_forward
- Construct a chromosome map from the following charts showing crossover frequencies for linkage groups on autosomes. (this one is tricky due to the unusual recombinations Gene Combinations Recombination Frequency y/w 2.2 v/m 3.0 v/r 26.6 v/w 30.0 v/y 32.2 w/m 33.0 y/m 35.2 w/r 56.6arrow_forwardThis karyotype is from a baby that was born alive but died shortly after birth. What condition is observed from this karyotype?arrow_forwardA geneticist determines that the order of four genes on a specific chromosome is CABD because the recombination frequencies were 35% for C-D, 24% for A-D, 23% for B-D, and 10% for A-B. What has the geneticist constructed?arrow_forward
- In Creighton and McClintock’s experiment demonstrating thatcrossing over involves physical exchange between chromosomes, explain the importance of the cytological markers(the translocated segment and the chromosome knob) in theexperimental rationale.arrow_forwardWhich type(s) of chromosomal aberrations will suppress recombination in heterozygotes? A.) paracentric inversion B.)pericentric inversion C.)Robertsonian translocation D.)reciprocal translocation E.)tandem duplicationarrow_forwardRice has a chromosome number of 2n = 24. If different euploids and anaeuploids are available in rice, identifythe chromosomal mutation, chromosome configuration, chromosome number, and/or type of gametes in each of the mutations below. Complete the table. Example: for 10B, the answer is "10 II + 2 I"arrow_forward
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