BIOLOGY W/CONNECT >IP<
11th Edition
ISBN: 9781259910487
Author: Raven
Publisher: MCG CUSTOM
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Chapter 6, Problem 2S
Phosphofructokinase functions to add a phosphate group to a molecule of fructose 6-phosphate. This enzyme functions early in glycolysis, an energy-yielding biochemical pathway discussed in chapter 7. The enzyme has an active site that binds fructose and ATP. An allosteric inhibitory site also binds ATP when cellular levels of ATP are very high.
a. Predict the
b. Predict the rate of the reaction if levels of cellular ATP are very high.
c. Describe what is happening to the enzyme when levels of ATP are very high.
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Students have asked these similar questions
Phosphofructokinase is an important control enzyme in the regulation of cellular respiration. Which of the following statements correctly describes phosphofructokinase activity?
a. It is inhibited by citrate, an intermediate of the citric acid cycle.
b. It catalyzes a reaction which increases the rate of the overall pathway.
c. It catalyzes an early step of glycolysis which has the lowest level of activation energy among the overall pathway.
d. It is activated by ATP.
e. It is inhibited by AMP.
The enzyme Phosphofructokinase (PFK) is a key regulator of glycolysis.
A) Does ATP bind the PFK allosteric siteor the active site?
B) Does high amount of ATP in the cell activate or inhibit PFK? Why?
C)What do you suppose happens to glucose if glycolysis is inhibited in the cell?
a. Starting with acetyl-CoA in the mitochondria, how many ATP molecules are needed to synthesize a 14 C fatty acid?
A. 3
B. 6
C. 9
D. 12
b. How many FADH2 molecules will be obtained from the complete oxidation of Myristic acid to CO2 ?
A. 13
B. 11
C. 15
D. 17
c. If the complete oxidation of a saturated fatty acid result in the production of 82 ATP molecules, how many ATP molecules will be obtained from a mono-unsaturated fatty acid of similar length?
A. 80.5
B. 82
C. 84.5
D. 83.5
Chapter 6 Solutions
BIOLOGY W/CONNECT >IP<
Ch. 6 - A covalent bond between two atoms represents what...Ch. 6 - During a redox reaction the molecule that gains an...Ch. 6 - Prob. 3UCh. 6 - A spontaneous reaction is one in which a. the...Ch. 6 - Prob. 5UCh. 6 - Which of the following is NOT a properly of a...Ch. 6 - Where is the energy stored in a molecule of ATP?...Ch. 6 - Prob. 1ACh. 6 - Which of the following statements is NOT true...Ch. 6 - Prob. 3A
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- Explain why some of the molecules are positioned away from the diagonal in the graph given below. What kind of processes are involved in this phenomenon? Moreover, explain differences and similarities between H-ATPases and H-PPases.arrow_forwardThe regulation of 1-phosphofructokinase occurs primarily by allosteric effectors, including ATP and ADP. Given that phosphofructokinase activity is necessary for glycolysis to proceed, predict what effect ATP would have. How about ADP?arrow_forwardWhich of the following is incorrect about the ATP synthase mechanism? a. It explains how ATP is hydrolyzed into ADP and Pi b. At any moment, each catalytic site has a different conformation and binding affinity c. It is called the binding change mechanism d. It involves rotation-driven conformational changes that alter the affinity of each catalytic subunitarrow_forward
- In a Lineweaver-Burk graph, the lines representing the uninhibited and inhibited enzyme catalyzed reaction meet each other on the x-axis. The type of inhibition which is occurring is: a) competitive b) noncompetitive c) uncompetitive d) allosteric CO2 exerts direct activity upon hemoglobin by: a) blocking oxygen from binding to the heme group b) displacing BPG from the central cavity c) oxidizing Fe+2 to Fe+3 which does not bind oxygen d) forming an N-terminal carbamate which favors the T-state The dominant motif found in hemoglobin and myoglobin is: a) helix-turn-helix b) twisted beta sheet c) beta barrel d) random coil Which of these is an ketohexose? a) fructose b) glucose c) ribose d) erythrose Which of these is a constitutional isomer of d-glucose? a) fructose b) galactose c) l-glucose d) ribose Which of these is an enantiomer of d-glucose? a) d-fructose b) d- galactose c) l-glucose d) d-ribose Which of these is a diastereomer of…arrow_forwardThe oxidation state of critical cofactors plays an important role in regulating cell metabolism. Which of the following correctly describes the relationship between oxidation states and a cellular process? A. An increased NAD+/NADH ratio will drive fatty-acid synthesis. B. An increased FADH2/FAD ratio will drive ATP production. C. A decreased FADH2/FAD ratio will increase the activity of ATP synthase. D. A decreased NADH/NAD+ ratio will drive fatty-acid oxidation. answer choice is D, can anyone explain to me why through catabolism and anabolism and energy I have not gone through glycolysis or krebs cycle, synthesis or oxidation yet so if someome could explain it in laymens terms that would be greatarrow_forwardRegarding phosphofructokinase, which of the following statements is true: a. Low [ATP] stimulates the enzyme, but fructose-2,6-bisphosphate inhibits. b. High [ATP] stimulates the enzyme, but fructose-2,6-bisphosphate inhibits. c. The enzyme is more active at low [ATP] than at high, and fructose-2,6-bisphosphate activates the enzyme. d. High [ATP] stimulates the enzyme, and fructose-2,6-bisphosphate activates.arrow_forward
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