Concept explainers
To explain: The reason how the exposure to DNP affects ATP synthesis by mitochondria.
Concept introduction: Dinitrophenol (DNP) is an uncoupling agent of oxidative phosphorylation that disrupts the H+ gradient, leading to decreased ATP synthesis. This increases the basal
To explain: How the use of dinitrophenol (DNP) could lead to weight loss in humans.
Concept introduction: Dinitrophenol (DNP) is an uncoupling agent of oxidative phosphorylation that disrupts the H+ gradient, leading to decreased ATP synthesis. This increases the basal metabolic rate and results in weight loss as more fats and carbohydrates are used. An uncoupler such as dinitrophenol will not affect the NADPH production in a chloroplast. The dinitrophenol will not affect the reduction of NADP+.
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