Human Physiology: An Integrated Approach (8th Edition)
Human Physiology: An Integrated Approach (8th Edition)
8th Edition
ISBN: 9780134605197
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Chapter 6.4, Problem 16CC
Summary Introduction

To determine: The ways in which insulin hormone have two different effects.

Introduction: The hormone that is responsible for enabling glucose to enter the cells is called the insulin hormone. The pancreas follows the stomach, and the cells of pancreas, which are called the Islets of Langerhans, help in the production of insulin.

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Name two proteins that are effectors of the insulin signaling pathway in adipocytes, liver, or muscle cells. Explain how these effector proteins address the conditions that triggered insulin release.
Based on your understanding of the binding of insulin, select all of the following events that you would expect to occur in muscle cells due to insulin binding to receptors.Group of answer choices a. Glycogen synthesis is activated b. PFK is stabilized in the R-state and glycolysis is activated  c. GLUT4 (transporters) are increased in concentration at the plasma membrane d. Fructose 2,6-bisphosphate increased levels aid in stabilization of the T-state fructose 1,6-bisphosphatase  e. Gluconeogenesis is activated in response to elevated fructose 2,6-bisphosphate levels f. Phosphorylation cascades allow for covalent modifications that would aid in the breakdown of glycogen to allow for increased levels of glucose 6-phosphate in the cell g. Hexokinase is inhibited so glucose will not be brought into the cell in high amounts h. Glycogen breakdown pathway is inactivated
Insulin is a peptide hormone that is lacking from the body in some forms of diabetes mellitus. Why do people with this type of diabetes inject insulin rather than consuming an insulin pill?

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Human Physiology: An Integrated Approach (8th Edition)

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