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Cardiopulmonary Anatomy & Physiolo...

7th Edition
Des Jardins + 1 other
ISBN: 9781337794909

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BuyFindarrow_forward

Cardiopulmonary Anatomy & Physiolo...

7th Edition
Des Jardins + 1 other
ISBN: 9781337794909
Textbook Problem

In chronic hypoventilation, renal compensation has likely occurred when the

1. HCO 3 - is higher than expected for a particular Pco 2

2. pH is lower than expected for a particular Pco 2

3. HCO 3 - is lower than expected for a particular Pco 2

4. pH is higher than expected for a particular Pco 2

A. 1 only

B. 2 only

C. 1 and 4 only

D. 3 and 4 only

Summary Introduction

Introduction:

The mechanism by which kidneys can regulate the pH (potential of hydrogen) of plasma is called renal compensation. It is an important mechanism for acid–base balance. The amount of carbon dioxide gas dissolved in the blood is reflected by the partial pressure of carbon dioxide (Pco2). This partial pressure of carbon dioxide plays a major role for this compensation to occur.

Explanation

Justification/explanation for the correct answer:

Option (C) states that the bicarbonate ion is higher than expected for a particular partial pressure of carbon dioxide. Chronic hypoventilation is defined as an increase in the partial pressure of carbon dioxide due to insufficient ventilation. This results in an increase in carbonic acid (H2CO3), bicarbonate ion (HCO3), and the partial pressure of carbon dioxide (Pco2). Renal compensation is done by the retention of HCO3, which occurs when HCO3 and pH are higher than expected for Pco2. Hence, option (C) is correct.

Explanation for the incorrect answers:

Option (a) states that only bicarbonate ion is higher than expected for a particular partial pressure of carbon dioxide

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