Concepts of Genetics Plus Mastering Genetics with Pearson eText -- Access Card Package (12th Edition) (What's New in Genetics)
12th Edition
ISBN: 9780134811390
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 8, Problem 5PDQ
What evidence suggests that Down syndrome is more often the result of nondisjunction during oogenesis rather than during spermatogenesis?
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Discuss whether the following individuals (1) have male or female gonads, (2) are phenotypically male or female (Wolffian or Muellerian ducts. External genitalia) and (3) are sterile or fertile.
a) XY, homozygous for a recessive mutation in the testosterone biosynthetic pathway, producing no testosterone
b) XX, heterozygous for a dominant mutation in the testosterone biosynthetic pathway, which causes continuous production of testosterone
Briefly describe nondisjunction in meiosis and identify several potential consequences. In other words, what are the possible outcomes?
a) Define Disorders of Sex Development (DSD).
b) Explain why gene mutations affecting gonad development may lead to DSD conditions.
c) What is sex-chromosome mosaicism? When and how may this mosaicism arise?
Chapter 8 Solutions
Concepts of Genetics Plus Mastering Genetics with Pearson eText -- Access Card Package (12th Edition) (What's New in Genetics)
Ch. 8 - A human female with Turner syndrome (47, X) also...Ch. 8 - When two plants belonging to the same genus but...Ch. 8 - What is the effect of a rare double crossover (a)...Ch. 8 - Controlling the overgrowth of invasive aquatic...Ch. 8 - Controlling the overgrowth of invasive aquatic...Ch. 8 - Controlling the overgrowth of invasive aquatic...Ch. 8 - HOW DO WE KNOW? In this chapter, we have focused...Ch. 8 - Review the Chapter Concepts list on page 171....Ch. 8 - Define these pairs of terms, and distinguish...Ch. 8 - For a species with a diploid number of 18,...
Ch. 8 - What evidence suggests that Down syndrome is more...Ch. 8 - What evidence indicates that humans with aneuploid...Ch. 8 - Contrast the fertility of an allotetraploid with...Ch. 8 - Describe the origin of cultivated American cotton.Ch. 8 - Predict how the synaptic configurations of...Ch. 8 - Inversions are said to suppress crossing over. Is...Ch. 8 - Contrast the genetic composition of gametes...Ch. 8 - Human adult hemoglobin is a tetramer containing...Ch. 8 - Discuss Ohnos hypothesis on the role of gene...Ch. 8 - What roles have inversions and translocations...Ch. 8 - The primrose, Primula kewensis, has 36 chromosomes...Ch. 8 - Certain varieties of chrysanthemums contain 18,...Ch. 8 - Drosophila may be monosomic for chromosome 4, yet...Ch. 8 - Mendelian ratios are modified in crosses involving...Ch. 8 - Having correctly established the F2 ratio in...Ch. 8 - The mutations called bobbed in Drosophila result...Ch. 8 - The outcome of a single crossover between...Ch. 8 - A couple planning their family are aware that...Ch. 8 - In a cross in Drosophila, a female heterozygous...Ch. 8 - A woman who sought genetic counseling is found to...Ch. 8 - Prob. 25ESPCh. 8 - In a recent cytogenetic study on 1021 cases of...Ch. 8 - A boy with Klinefelter syndrome (47,XXY) is born...Ch. 8 - Prob. 28ESPCh. 8 - A 3-year-old child exhibited some early indication...Ch. 8 - A normal female is discovered with 45 chromosomes,...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Give the chromosomal constitution & related sex in each of the following :-i) Turner syndromeii) Klinefilter syndromearrow_forwardWhat are the Consequences of Inversions during Gamete Formation ?arrow_forwardWhich is the type ofgamete produced by aheterozygous individual?What is the genotypicalproportion of these gametes?arrow_forward
- With reference to sex determination in humans, discuss: i) X chromosome inactivation; and ii) Testicular feminizationarrow_forwardIt has been suggested that looking for the presence of the SRY gene would be a better way of determining whether she is “male” or “female”. Is this accurate? Please explain. Also, does she possess ovaries? Testes? Both? Neither?arrow_forwardDraw a schematic diagram showing spermatogenesis vis-à-vis oogenesis. Label the stage of development and chromosome number of daughter cells at the following levels of maturation: (a) mitotic proliferation (b) meiosis I and II (c) maturation. Table 2: Spermatogenesis vis-à-vis Oogenesis Spermatogenesis Oogenesisarrow_forward
- In Figure 17-12, what would be the constitution of an individual formed from the union of a monosomic from afirst-division nondisjunction in a female and a disomicfrom a second-division nondisjunction in a male, assuming the gametes were functional?arrow_forwardIf nondisjunction of the sex chromosomes takes place in meiosis I in the male, what sexual phenotypes and proportions of offspring will be produced?arrow_forwardWhy is it necessary for gametogenesis to reduce the chromosome number of the sex cells by one-half?arrow_forward
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