BIOLOGY -LAB.MAN. >CUSTOM<
12th Edition
ISBN: 9781259754661
Author: Mader
Publisher: MCG CUSTOM
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Chapter 9, Problem 3TS
BPA is a chemical compound that has historically been used in manufacture of plastic products. However, cells often mistake BPA compounds for that accelerate the cell cycle. Because of this, BPA is associated with an increased riskof certain cancers.
a. How might BPA interact with the cell cycle and its checkpoints?
b. Why do you think that very small concentrations of BPA might have a large effect on cell?
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Students have asked these similar questions
a. Why are cell cycle checkpoints important?
b. What happens to a cell that fails to meet the requirements of a checkpoint and is not able make the necessary improvements or repairs?
Part A and B
A. What is the normal function of the Rb protein?
A) Rb prevents the cell cycle from proceeding unless the cell is prepared to do so
B) Rb causes cells to undergo apoptosis
C) Rb promotes Cdk activation
D) Each of the other selections is true
E) Rb repairs damaged DNA
B. How do tumors arise?
A) When cell proliferation occurs at a higher rate than cell death
B) When someone is infected with a tumor from another person
C) When cell death occurs at a very high rate
D) When cell proliferation occurs at a very low rate
Explain why we can say that M-phase of the cell-cycle is triggered by a positive feedback loop.
a) What would the consequences be if cohesins were working normally but condensins were not? and b) what stage of the cell cycle would this cause problems in?
Why is it important for the centrosome to duplicate during G1-G2 (interphase) before M phase?
The kinetochores serve as a link between the sister chromatids and the microtubules attached to the mitotic spindle. a) How are microtubules still able to exhibit dynamic instability after they are bound to the sister chromatids and b) why is this important to mitosis?
As the name suggests, the Anaphase-promoting-complex (APC), promotes the 4th phase of mitosis by separating the sister chromatids so they can travel to separate poles of the cell, and prevents them from being re-zipped together. Describe how APC does these two things (Hint: one involves M-cyclin and the other involves…
Chapter 9 Solutions
BIOLOGY -LAB.MAN. >CUSTOM<
Ch. 9.1 - 1. List, in order, the stages of the cell cycle...Ch. 9.1 - 2. Explain what conditions might cause a cell to...Ch. 9.1 - Discuss how apoptosis represents a regulatory...Ch. 9.2 - Prob. 1CYPCh. 9.2 - List the stages of chromosome compacting, starting...Ch. 9.3 - Prob. 1CYPCh. 9.3 - Prob. 2CYPCh. 9.3 - Discuss the importance of stem cells in the human...Ch. 9.4 - Prob. 1CYPCh. 9.4 - Prob. 2CYP
Ch. 9.4 - Prob. 3CYPCh. 9.5 - Prob. 1CYPCh. 9.5 - Prob. 2CYPCh. 9 - 1. What is the potential effect of abnormally high...Ch. 9 - 2. Why might some cancers be associated with a...Ch. 9 - Prob. 2NS.1QCCh. 9 - Prob. 2NS.2QCCh. 9 - Prob. 1ACh. 9 - Prob. 2ACh. 9 - Prob. 3ACh. 9 - Prob. 4ACh. 9 - Prob. 5ACh. 9 - Prob. 6ACh. 9 - Prob. 7ACh. 9 - Prob. 8ACh. 9 - Prob. 9ACh. 9 - Prob. 10ACh. 9 - Prob. 11ACh. 9 - Prob. 12ACh. 9 - Prob. 13ACh. 9 - Prob. 14ACh. 9 - Prob. 15ACh. 9 - Prob. 1TSCh. 9 - 2. The survivors of atomic bombs that were dropped...Ch. 9 - BPA is a chemical compound that has historically...Ch. 9 - Prob. 4TS
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Maturation promoting factor, MPF, is a cyclin-CDK complex that catalyzes the phosphorylation of other proteins to start mitosis. The activity level of MPF is dependent on the relative concentrations of the cyclin and CDK components of MPF (Figure 1). Based on Figure 1, which of the following describes the role of cyclin in the regulation of the cell cycle? a.During S phase, the cyclin level remains the same because DNA replication is occurring. b.During G2 phase, the cyclin level remains low, causing MPF activity to decrease, which leads cells to initiate mitosis. c.During G1 phase, the cyclin level decreases to signal the start of the resting phase of the cell cycle. d.During M phase, the cyclin level peaks, resulting in an increased binding frequency with CDK.arrow_forward(a) the cell cycle is divided into different phases (referred to as M, G0, G1, S and G2); Can you account for what happens during the different parts of the cycle and out of it is checked? ( b) What is the difference between apoptosis and necrosis? ( c) What are caspases and what is their function in the cell?arrow_forwardBPA is a chemical compound that has historically been used in themanufacture of plastic products. However, cells often mistake BPAcompounds for hormones that accelerate the cell cycle. Because ofthis, BPA is associated with an increased risk of certain cancers. Question: How might BPA interact with the cell cycle and its checkpoints?arrow_forward
- Scientists are able to isolate cells in various phases of the cell cycle. During an experiment in which Dr. Patrick McGroyn is causing cultured tumor cells to go through mitotic cell division, he isolates a group of cells that contain one and a half times more DNA than cells isolated in the G1 phase have. What phase must these cells be in? How do you know?arrow_forwardBenign and cancerous tumors occur when the cell cycle control mechanisms no longer operate correctly. What types of genes may be involved in these cell cycle control mechanisms?arrow_forwardResearchers studying cell cycle regulation in budding yeast have observed that a mutation in the CDC15 gene causes cell cycle arrest in telophase when the yeast cells are incubated at an elevated temperature. Which of the following statements best predicts the effect of the cell cycle arrest on proliferating yeast cells? A. Restate the question and record the right answer. B. Why is this the correct answer?arrow_forward
- What aspects of the cell cycle are controlled by the G1, G2, and M checkpoints? How are cyclins and cyclin-dependent protein kinases involved in cell cycle regulation at checkpoints?arrow_forward"Agent V" is the name of an anticancer (chemotherapy) drug. This drug works against cancer cells by inhibiting the formation of microtubules in sensitive cells. Consider a cell that is sensitive to agent V (in other words, agent V is effective at stopping growth of this cell). Based on this information, agent V would cause the cell to be frozen at which of the major cell cycle checkpoints (G1, G2 or M checkpoint)? Explainarrow_forwardDescribe the likely consequences of bypassing the G1 and G2 checkpoints in the cell cycle. Why do compounds like nonylphenol lead to the multiplication of abnormal cells?arrow_forward
- Mitotic nondisjunction can occur, particularly in tumor cells. Assume a single nondisjunction event involving the X chromosome occurs in a cell undergoing mitosis in a human female. First, consider the daughter cell with the smaller number of chromosomes: How many total chromosomes will this cell have? How many X chromosomes will this cell have? Next, consider the daughter cell with the larger number of chromosomes: How many total chromosomes will this cell have? How many X chromosomes will this cell have?arrow_forwardIn the mitosis experiment, in what stage were most of the onion root tip cells in? Based on what you know about cell cycle division, what does this imply about the life span of a cell? Were there any stages of the cell cycle that you did not observe? How can you explain this using evidence from the cell cycle?arrow_forwardOne important biological effect of a large dose of ionizing radiation (like X-rays) is to halt cell division. How does this occur? To answer this question, state the name and role of 2 specific and important proteins involved in the process. What happens if a cell has a mutation that prevents it from halting cell division after be irradiated? Be specific and detailed. An adult human who has reached maturity will die within a few days of receiving a radiation dose large enough to stop cell division. What does that tell you about cell division? In addition, name 2 different/unique cell types that would be primarily affected.arrow_forward
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cell division of meiosis and mitosis; Author: Stated Clearly;https://www.youtube.com/watch?v=A-mFPZLLbHI;License: Standard youtube license