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(a)
Interpretation:
A multi-step synthesis has to be designed for the given conversion.
Concept Introduction:
Target molecule is nothing but the desired product.
Adding
The elimination reaction should be carried out under SN2 condition i.e. with strong nucleophile. So there will be no compensating substitution reaction.
The bulky base is used in the elimination reaction to maximize the amount of elimination product.
To prepare cyclic ether, the
Addition of water to the given starting material creates bifunctional compound.
(b)
Interpretation:
A multi-step synthesis has to be designed for the given conversion.
Concept Introduction:
Target molecule is nothing but the desired product.
Adding
The elimination reaction should be carried out under SN2 condition i.e. with strong nucleophile. So there will be no compensating substitution reaction.
The bulky base is used in the elimination reaction to maximize the amount of elimination product.
To prepare cyclic ether, the alkyl halide and alcohol must be a part of the same molecule.
Addition of water to the given starting material creates bifunctional compound.
(c)
Interpretation:
A multi-step synthesis has to be designed for the given conversion.
Concept Introduction:
Target molecule is nothing but the desired product.
Adding
The elimination reaction should be carried out under SN2 condition i.e. with strong nucleophile. So there will be no compensating substitution reaction.
The bulky base is used in the elimination reaction to maximize the amount of elimination product.
To prepare cyclic ether, the alkyl halide and alcohol must be a part of the same molecule.
Addition of water to the given starting material creates bifunctional compound.
(d)
Interpretation:
A multi-step synthesis has to be designed for the given conversion.
Concept Introduction:
Target molecule is nothing but the desired product.
Adding
The elimination reaction should be carried out under SN2 condition i.e. with strong nucleophile. So there will be no compensating substitution reaction.
The bulky base is used in the elimination reaction to maximize the amount of elimination product.
To prepare cyclic ether, the alkyl halide and alcohol must be a part of the same molecule.
Addition of water to the given starting material creates bifunctional compound.
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Chapter 9 Solutions
EBK ORGANIC CHEMISTRY
- Propose an efficient multistep synthesis for the transformation shown below. There is no need to show the mechanism of any step, only the reagents required for each step, and the resulting intermediate product of each step. 1ouborq sto vino noib restriction: The given reactant is your only source of carbon atoms, but you may use more than one molecule of the reactant. multiple steps + en. OaTarrow_forwardPlease help with the following: Propose a synthesis of the following molecule from the given starting material. If more than one step is necessary, be sure to number separate steps.arrow_forwardDraw a possible forward synthesis to form the following compounds using MeOH, ETOH, NaCN and benzene as the only carbon sources. You can use any other reagents so long as they are not a source of carbon in the target molecule. A synthesis may use any previous compound as a reagent. Use retrosynthetic analysis to help. There may be more than one correct answer to each problem. НО Но OH j) k) h) HNarrow_forward
- Predict the major product for the following reaction. بیگ مرمو ? Modify the given structure of the starting material to draw the major product.arrow_forwardWhat would be the optimal conditions to achieve the following synthesis? дон dilute H₂SO4 concentrated H₂SO4 dilute HBr concentrated HBr aqueous NaOHarrow_forwardComplete the following synthesis by selecting from the list of 10 reagents below. Each reagent (or set of reagents) is labeled as a letter. In the answer box, simply place the order of reagents used as uppercase letters. For example, if your synthesis involves using reagent A followed by B,followed by C, and then D, your answer would be: ABCD.arrow_forward
- 5) Show a reasonable synthesis for the following reaction. The reaction can be completed in 3 steps. Draw a reasonable (and complete) mechanism for the first transformation and the last transformation. Name the type of reactions for each step. HO OH OH CHOarrow_forwardPropose how the following molecules can be synthesized from the illustrated starting material. Draw all reactants, reagents, catalysts, and other components necessary for each step.arrow_forwardHow reach this target molecule?arrow_forward
- How would you use this reaction for the following synthesisarrow_forwardProvide the reagents necessary to carry out the synthesis. Draw out the mechanism used in the synthesis belowarrow_forwardSelect the correct reagents to carry out the following multi-step synthesis. CH3 CH2-Br CH,-OH CHO step 1 step 2 step 3 step 4 step 2 NJOH step 3 PCC CHICI, AICI3 step 4 N8S step 1 n the others.arrow_forward
- Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning
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