In Exercises 9–20, assume that the paired sample data are simple random samples and that the differences have a distribution that is approximately normal.
18. Before/After Treatment Results Captopril is a drug designed to lower systolic blood pressure, when subjects were treated with this drug, their systolic blood pressure readings (in mm Hg) were measured before and after the drug was taken. Results arc given in the accompanying table (based on data from “Essential Hypertension: Effect of an Oral Inhibitor of Angiotensin-Convening Enzyme,” by MacGregor et al., British Medical Journal, Vol. 2). Using a 0.01 significance level, is there sufficient evidence to support the claim that Captopril is effective in lowering systolic blood pressure?
Subject | A | B | C | D | E | F | G | H | I | J | K | L |
Before | 200 | 174 | 198 | 170 | 179 | 182 | 193 | 209 | 185 | 155 | 169 | 210 |
After | 191 | 170 | 177 | 167 | 159 | 151 | 176 | 183 | 159 | 145 | 146 | 177 |
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