Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter CHST2, Problem 3DQ
In many cases, ncRNAs serve as “guides” to direct proteins to other
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Chapter CHST2 Solutions
Essentials of Genetics (9th Edition) - Standalone book
Ch. CHST2 - What are some of the different roles that RNA...Ch. CHST2 -
2. What arguments support the RNA World...Ch. CHST2 - Prob. 3RQCh. CHST2 - How is bacterial DNA methylation and expression of...Ch. CHST2 - What are the three types of small noncoding RNAs...Ch. CHST2 - The mechanism for RNA-induced transcriptional...Ch. CHST2 - Although exRNAs are found in many fluids within...Ch. CHST2 - How and why are eukaryotic mRNAs transported and...Ch. CHST2 - The RNA World Hypothesis suggests that the...Ch. CHST2 - Bacterial sRNAs can bind to mRNAs through...
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- a) The deacetylation of histones generally causes gene inactivation. True or false? b)During eukaryotic translation, the first contact between the ribosome and the mRNA is usually made when the small ribosomal subunit directly binds to the translational start site (Kozak sequence) on the mRNA. True or false? c)The termination of translation is carried out by a single tRNA molecule that recognizes all three stop codons. True or false? d) The deamination of cytosine, which produces uracil, is less likely to be repaired, compared to the deamination of 5-methylcytosine, which produces thymine.True or false? e)An HLH-bHLH heterodimer can bind DNA. True or false? F)Chromatin remodeling complexes posseses ATPase activity. True or false? g)Histone methylation generally causes gene inactivation. True or false? h) A pre-mRNA is cleaved downstream of its polyA signal before the transcription terminates. True or false? i) During X chromosome inactivation in female mammals, most genes are repressed…arrow_forwardBriefly describe the role of the following RNAS: (i) IncRNA (ii) miRNAarrow_forwardList and briefly describe four types of molecules that can bind to an ncRNA.arrow_forward
- Knowing that the genetic code is almost universal, a scientist uses molecular biological methods to insert the human β-globin gene (Shown in Figure 17.11) into bacterial cells, hoping the cells will express it and synthesize functional β-globin protein. Instead, the protein produced is nonfunctional and is found to contain many fewer amino acids than does β-globin made by a eukaryotic cell. Explain why.arrow_forwardThe 5′ region of the TPP riboswitch in Bacillus subtilis is very similar to the TPP riboswitch in E. coli. Even so, the riboswitch in B. subtilis regulates transcription, whereas the one in E. coli regulates translation. What is the role of the 5′ region in both riboswitches? How can one riboswitch regulate transcription while the other regulates translation?arrow_forwardThe number of microRNAs encoded by the genome varies widely among organisms: some species have many miRNA genes and other species have relatively few. Researchers have determined the number of miRNA genes possessed by different species and have made the following observations: Q. The number of miRNA genes found on a chromosome is not correlated with chromosome length. In other words, longer chromosomes do not necessarily have more miRNA genes.arrow_forward
- 1) Considering how readily RNA folds to form a secondary structure, why isn’t it used to store genetic information rather than double-stranded DNA? Cite multiple reasons. 2) Do miRNA and siRNA both derive from the same source? Explain.arrow_forwardShown below is a double-stranded bacterial (E. coli) DNA sequence coding for a hypothetical protein. The nucleotides are numbered 1 to 100. a)Although the transcription start site begins at the underlined C/G, which of the following is the nucleotide sequences needed upstream for transcription to actually occur? b)What are the first 15 nucleotides of the mRNA? c)What are the first 5 amino acids translated from the resulting mRNA? d)A different mutation results in the substitution of the T/A base pair at position 30 (shown in bold and underlined) with a G/C base pair. How would this mutation affect the sequence of the protein that is produced?arrow_forwardThe number of microRNAs encoded by the genome varies widely among organisms: some species have many miRNA genes and other species have relatively few. Researchers have determined the number of miRNA genes possessed by different species and have made the following observations: a. The number of miRNA genes found on a chromosome is not correlated with chromosome length. In other words, longer chromosomes do not necessarily have more miRNA genes. b. Most species show a strong positive correlation between the number of miRNA genes on a chromosome and the number of non-proteinencoding genes on that chromosome. In other words, chromosomes with more non-protein-encoding genes have more miRNA genes. c. Many species display a strong positive correlation between the number of miRNA genes on a chromosome and the number of protein encoding genes on that chromosome. In other words, chromosomes with more protein-encoding genes have more miRNA genes Propose possible explanations for these…arrow_forward
- The number of microRNAs encoded by the genome varies widely among organisms: some species have many miRNA genes and other species have relatively few. Researchers have determined the number of miRNA genes possessed by different species and have made the following observations: a. The number of miRNA genes found on a chromosome is not correlated with chromosome length. In other words, longer chromosomes do not necessarily have more miRNA genes. b. Most species show a strong positive correlation between the number of miRNA genes on a chromosome and the number of non-proteinencoding genes on that chromosome. In other words, chromosomes with more non-protein-encoding genes have more miRNA genes. c. Many species display a strong positive correlation between the number of miRNA genes on a chromosome and the number of proteinencoding genes on that chromosome. In other words, chromosomes with more protein-encoding genes have more miRNA genes. Propose possible explanations for these…arrow_forwardA normal hemoglobin protein has a glutamic acid at position 6; in sickle-cell hemoglobin, this glutamic acid has been replaced by a valine. List all the possible mRNA codons that could be present for each type of hemoglobin. Can a single base change result in a change from Glu to Val in hemoglobin?arrow_forwarda) What is a mutation in molecular terms? b) a mutation deletes a base in the genomic DNA discuss how that will affect the reading frame and expression product production. Using the following list of codons describe, using diagrams etc., how information stored in the DNA is translated into a peptide. Be sure to discuss all steps. In other words, use a diagram and give me sequences, transcription and translation steps. Show the sequences of the sense and the other DNA strand, the mRNA and the tRNA’s. UUU -phenylalanine UCU -serine AUG –initiation/methionine CUU -leucine ACU -threonine GUU -valine UAA -Terminationarrow_forward
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