Genetic Analysis: An Integrated Approach Plus Mastering Genetics with Pearson eText -- Access Card Package (3rd Edition) (What's New in Genetics)
3rd Edition
ISBN: 9780134807799
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter D, Problem 11P
In Island Melanesia and Polynesia, most mtDNA haplotypes are of Asian ancestry, whereas Y chromosome haplotypes are predominantly New Guinean. Provide a hypothesis for this sex
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An allele of the G6PD gene acts in a recessive manner to cause sensitivity to fava beans, resulting in ahemolytic reaction (lysis of red blood cells) afteringestion of the beans. The same allele also confersdominant resistance to malaria. The heterozygote hasan advantage in a region where malaria is prevalent.Will the equilibrium frequency (qe) be the same foran African and a North American country? Whatfactors affect qe?
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Chapter D Solutions
Genetic Analysis: An Integrated Approach Plus Mastering Genetics with Pearson eText -- Access Card Package (3rd Edition) (What's New in Genetics)
Ch. D - Why might mitochondrial, Y chromosome, and...Ch. D - What insights have analyses of human mitochondrial...Ch. D - What lines of evidence support the hypothesis that...Ch. D - Discuss how both gains and losses of regulatory...Ch. D - D.5 How do copy number variants arise? Do they...Ch. D - Consider possible societal and ethical dilemmas...Ch. D - Prob. 7PCh. D - Describe how selection at a locus can result in a...Ch. D - D.9 How can ancient DNA provide insight into past...Ch. D - D.10 Denisovans are known from bones found in...
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- Two alleles have been found at the X-linked phosphoglucomutase gene (Pgm) in a Drosophila persimilispopulation in California. The frequency of the PgmAallele is 0.25, while the frequency of the PgmBalleleis 0.75. Assuming the population is at Hardy-Weinbergequilibrium, what are the expected genotype frequencies in males and females?arrow_forwardTwo SNPs are located in the short arm of chromosome 12. SNP1 has allele frequencies of 60% T and 40% C, and SNP2 has allele frequencies of 40% A and 60% G. What is the frequency of the haplotype T-G in a population if the two SNPs are in absolute linkage disequilibrium and if they are in linkage equilibrium?arrow_forwardConsider two blood polymorphisms that humans have in addition to the ABO system. Two alleles LM and LN determine the M, N, and MN blood groups. The dominant allele R of a different gene causes a person to have the Rh+ (rhesus positive) phenotype, whereas the homozygote for r is Rh− (rhesus negative). Two men took a paternity dispute to court, each claiming three children to be his own. The blood groups of the men, the children, and their mother were as follows:From this evidence, can the paternity of the children be established?arrow_forward
- Identify each of the following as an example of allele, genotype,and/or phenotype frequency:A. Approximately 1 in 2500 individuals of Northern Europeandescent is born with cystic fibrosis.B. The percentage of carriers of the sickle cell allele in WestAfrica is approximately 13%.C. The number of new mutations per generation resultingin achondroplasia, a genetic disorder, is approximately5 × 10−5.arrow_forwardOrange coat color in cats is due to an X-linked allele (XO) that iscodominant with the allele for black (X+). When genotypes at the orangelocus were determined for a sample of cats in Minneapolis and St. Paul,Minnesota, the following data were obtained:XOXO females 11XOX+ females 70X+X+ females 94XOY males 36X+Y males 112Calculate the frequencies of the XO and X+ alleles for this population.arrow_forwardA total of 1000 members of a Central American population are typed for the ABO blood group. In the sample, 421 have blood type A, 168 have blood type B, 336 have blood type O, and 75 have blood type AB. Part A Use this information to determine the frequency of ABO blood group alleles in the sample. Recall that when considering genes with three alleles whose frequencies are represented by the variables p, q, and r, the sum of genotype frequencies resulting from trinomial expansion is: (p+q+r)² =p² + 2pq+q2+2pr+r²+2gr = 1arrow_forward
- The prevalence (frequency) of sickle-cell disease in Canada is quite low, affecting 1/3800 individuals. However, in some African populations 1/25 individuals are affected by sickle-cell disease. The difference in frequency of this allele within the differing populations has to do with the adaptation pressures that exist in the different environments. Individuals with the heterozygous genotype have a survival advantage in environments where the disease malaria is prevalent as the presence of this mutant allele leads to resistance to malaria. Therefore, the sickle-cell disease tends to be more frequent in environments where the malaria parasite is most common. Question: Explain why the sickle-cell disease remains frequent in some populations while it exists in very low frequency in other populations.arrow_forwardFor each of the following, identify what characteristics of a species male and female karyotype would indicate that mechanism of sex-determination. In each case, list a characteristic that would be specific to only that sex-determination system if possible. If no such characteristic is possible, specify which other sex-determination system would show the same karyotype characteristic. (A) Genic (B) XY sex chromosomes (C) ZW sex chromosomes (D) Haplo-diploid genomes (E) XO sex chromosomes (F) Environmentalarrow_forwardColor blindness in humans is an X-linked recessive trait. Approximately10% of the men in a particular population are color blind.a. If mating is random with respect to the color-blindness locus, what isthe frequency of the color-blindness allele in this population?b. What proportion of the women in this population are expected to becolor blind?c. What proportion of the women in this population are expected to beheterozygous carriers of the color-blindness allele?arrow_forward
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