Creatine kinase

Actions and Effects of Creatine Throughout time, humans have had a fascination with being excellent at what they do, and athletics have been no exception. Many substances exist, and many have been criticized and analyzed for their safety, legality, and morality for athletes. With the banning of steroids from competitive sports, and the implementation of random drug testing in most sports, most athletes, professional, recreational, and would-be professionals are hoping

transformation of creatine into energy occurs within the first few seconds of exertion. Creatine supplements are artificially made creatine that can be taken by athletes as ergogens, substances that can be used by athletes to enhance performance. Artificially made creatine is available as powder, capsules, candy, and gum. The goal of creatine supplementation is to increase the energy in the muscles so that athletes can improve their strength, speed, and endurance.   Although creatine is fairly

significant presence in the athletic industry within the last couple decades. One of the most popular performance enhancing supplements is creatine. One may ask, “why take creatine supplements if our body produces it and you can find it, naturally, in animal foods?” On average, intake of creatine,

Literature Review: Creatine Supplementation Introduction Creatine is a natural substance that occurs in the body, it is also a supplement that has been tested by numerus athletes over the years to see whether it has a positive effect on performance. However, there is anecdotal evidence that suggests creatine supplementation may be the cause of negative side effects such as dehydration, the increase of muscle cramping and an increase in blood pressure. One way the supplementation of creatine can improve

Date: 08/22/16 Formal Write-Up #2 CC: New OB HPI: YM is a 24 year old G2P1 who presents for New OB Visit at 28 weeks 6 days. Her concerns are the following: 1. Diarrhea – The patient reports traveling to Hawaii approximately 3 weeks ago. She returned home with loose stools. She had a stool sample that showed positive parasites, and was subsequently started on Metronidazole. She finished that course of antibiotics. After that, she continued to have persistent diarrhea. She was worked up for

Introduction Cushing’s syndrome(CS) results from prolonged exposure to excess free glucocorticoids. Around 10-15 per million people are affected by CS every year(1). Most patients with CS have an Adrenocorticotrophic(ACTH)- secreting pituitary adenoma, which is otherwise known as Cushing’s disease. Other causes of CS include adrenal tumours, ectopic ACTH-secreting tumours and exogenous steroid use. Except for exogenous steroid use, the other mentioned causes of CS can all be caused by genetic mutations

3. Results 3.1. Identification and characterization of three GS isoforms Three different GS sequences (GS01, GS02 and GS03) have been identified through the sequencing and blastx searching. All the sequences contain a complete coding sequence (CDS) region and 5′ and 3′-UTRs. In this study we have attempted the characterization of the multiple GS cDNAs present. The characteristics details of the full-length cDNAs of GS01 (Accession No. JQ740737), GS02 (Accession No. JQ740738) and GS03 (Accession No

Bromophenols have been identified as potential therapeutics for treating type 2 diabetes mellitus (T2DM) due to their suspected tyrosine phosphatase 1B (PTP1B) inhibitory activity. A new series of bromophenol analogues will be synthesised and their PTP1B inhibitory activity will be tested in in vitro enzymatic assays to elucidate their mechanism of action as PTP1B inhibitors. Background and Introduction Type 2 diabetes mellitus (T2DM) is a metabolic disease that is caused by insulin resistance

histone phosphorylation by recombinant PKC1 was measured in absence or presence of lipids. Without lipids, Pkc1 activity was 31.5 pmol/min/mg. When DAG subspecies were added, Pkc1 activity increased up to two fold (Fig. 3A). In order to make sure kinase activity measured was specific to Pkc1, APP1 activity was measured when exposed to DAG subspecies and as expected, did not cause phosphorylation of histone, which was expected (Fig. 3B). When phytoceramide lipids were added, Pkc1 activity decreased

oncogene, which becomes fused to the breakpoint cluster region (bcr) in the Philadelphia chromosome, following translocation. Presence of this bcr-abl gene fusion produces a poorly regulated tyrosine kinase, which results in a much higher level of cell proliferation. The action of this tyrosine kinase results in chronic myelogenous leukemia (CML) symptoms, such as overproduction of white blood cells. 2) Opposed to structural data alone, NMR