has been named as a toxic gas since its discovery in 1713, and only in the late 80’s of the past century scientist and researchers were capable to determine quantities of endogenous H2S in animals brain [1-3]. Yet recent; number of fundamental investigations were able to illustrate the physiochemical properties of the H2S as a reducing agent and nucleophile, which affords its ability to scavenge reactive oxygen species (ROS). Another essential field of research addressed cytoprotective properties
significant elevation in serum levels of urea and creatinine which reflects a marked impairment of the kidney function. Such results were reported by the previous studies [35], which documented that serum levels of urea and creatinine are good markers of nephrons functional capacity. However, the serum level of creatinine is a more indicative than the urea concentration in the first phases of kidney disease, while the level of urea begins to increase only after the
Lungs Lesions of lungs comprise lymphangioleiomyomatosis (LAM) and multinodular multifocal pneumocystis hyperplasia (MMPH) which are present in round 1/3 mature women and rarely in males [1]. AML cells can migrate to the lungs causing proliferation of smooth muscle and progressive destruction of pulmonary parenchyma, resulting in a potentially fatal pulmonary disease known as lymphangioleiomyomatosis (LAM) [9]. Heart Rhabdomyomas are benign tumors of striated muscle, rarely observed in non-TSC-affected
The Middle East respiratory syndrome coronavirus (MERS-CoV) is a positive-strand RNA virus belonging to the C lineage of the Betacoronavirus genus. Since its identification in 2012 in a patient from Saudi Arabia, there have been seven hundred one laboratory-confirmed cases of MERS-CoV in eight different countries, boasting an alarming thirty-five percent patient fatality rate. Both alphacoronaviruses (alphaCoVs) and betacoronaviruses (betaCoVs) have been known to cause human disease, but a majority
a species' usage and knowledge of tools and crafts, and how it affects a species' ability to control and adapt to its environment (Science vs Technology, 2017). Today, the essential importance of science is mostly constrained to observational investigation including utilization of the logical strategy. Technology can be connected either largely or to particular territories: examples incorporate development Technology, therapeutic Technology, or cutting edge Technology. At its simplest, biotechnology
of the lysosomal hydrolases. However, unlike any other enzyme there are two differently sized polypeptides which are differentially distributed in tissues. In tissues like brain the smaller polypeptide (molecular weight = 80 KDa) is found, whereas kidney contains both the polypeptides (110 and 80 KDa). There is no precise explanation for the occurrence of single differently sized polypeptides in some tissues, and the presence of both forms in tissues
determine its internal structure and as an aid to discerning the functions and relationships of its components” (Dissection). The term is most often used concerning the dissection of plants and animals, including humans. Comparative anatomy is the investigation of similitudes and contrasts in the life structures of various species. It is firmly identified with transformative science and phylogeny. Comparative anatomy has gradually and long been utilized as evidence for evolution; it indicates that various
The possibility of transplanting organs and tissue between species has long been a fantasy for many researchers, scientists, doctors and patients. Xenotransplantation has been traced back to the 1700’s when doctors tried to replace failing human organs with the organs from pigs, goats, lambs or even monkeys, however all of these attempts have failed. Pig insulin was also used to treat diabetics in the 1930’s (PBS, 2017). As a result of these consecutive failed attempts doctors were forced to abandon
Introduction: Our environment contains countless contaminants such as bacteria, toxins, virus and parasites, many of which pose a direct threat to the wellbeing of the host. As such, multicellular organisms have evolved specific mechanisms to protect from the extensive threats that would otherwise cause disease and possibly death. The most basic and primordial defense mechanism employed by such hosts is that of antimicrobial peptides (AMP) that possess the ability to preferentially bind to
1. Introduction Food fraud is a serious issue which has come under increased scrutiny as a potential food safety and public health concern in recent years (Spink and Moyer 2011). Regulators, food producers, retailers, and consumers all have an interest in safeguarding foods and ensuring they are safe, genuine, and of the highest quality. Nevertheless, food fraud has been conducted since ancient times, with evidence of laws dating back to Roman times regarding the adulteration of wine, through the