. (a) Explain the biochemical basis for the fact that one can synchro- nize cell populations by treating them with deoxythymidine. (b) Explain the apparent paradox that DATP at low concentrations is an activator of ribonucleotide reductase, whereas at higher concen- trations it becomes inhibitory.
. (a) Explain the biochemical basis for the fact that one can synchro- nize cell populations by treating them with deoxythymidine. (b) Explain the apparent paradox that DATP at low concentrations is an activator of ribonucleotide reductase, whereas at higher concen- trations it becomes inhibitory.
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter26: Synthesis And Degradation Of Nucleotides
Section: Chapter Questions
Problem 6P: Allosteric Regulation of Ribonucleotide Reductase by ATP and Deoxynucleotides Describe the...
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