20. Fill in this table with the effects that this mutation would have on mRNA and protein sequence and pro- duction. For "MRNA sequence" and "protein sequence", I am asking if the structure of these molecules (i.e., their sequence) changes. For "# of mRNA molecules" or "# of protein molecules", I am asking of the expression of these genes (i.e., how much mRNA or protein will be made) changes. It doesn't matter if the protein or DNA works or not. Assume each mutation is homozygous. # of mRNA protein # of protein protein molecules mRNA sequence molecules sequence function (best guess!) a mutation in promoter that leads to stronger binding of RNA polymerase a mutation in silencer that leads to weaker binding of repressor transcription factor a mutation in enhancer that leads to weaker binding of acti- vator transcription factor

20. Fill in this table with the effects that this mutation would have on mRNA and protein sequence and pro- duction. For "MRNA sequence" and "protein sequence", I am asking if the structure of these molecules (i.e., their sequence) changes. For "# of mRNA molecules" or "# of protein molecules", I am asking of the expression of these genes (i.e., how much mRNA or protein will be made) changes. It doesn't matter if the protein or DNA works or not. Assume each mutation is homozygous. # of mRNA protein # of protein protein molecules mRNA sequence molecules sequence function (best guess!) a mutation in promoter that leads to stronger binding of RNA polymerase a mutation in silencer that leads to weaker binding of repressor transcription factor a mutation in enhancer that leads to weaker binding of acti- vator transcription factor

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter16: Regulation Of Gene Expression

Section: Chapter Questions

Problem 6TYK

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Discuss Concepts The normal form of a gene contains the nucleotide sequence: When this gene is transcribed, the result is the following mRNA molecule: In a mutated form of the gene, two extra base pairs (underlined) are inserted: What effect will this particular mutation have on the structure of the protein encoded in the gene?
1. Bradykinin peptide: a) The sequence of the gene that encoded it, indicating with different colors, the direction, its components and the part of the cell where it occurs with the name of this stage. b) The sequence of the mature mRNA, indicating with different colors the structure of its components and the site of the cell with the name of the stage where it occurs. c) Mention the site of the cell where the bradykinin peptide was synthesized. d) In the DNA sequence make a point mutation by substitution, indicate with a different color the site and the effect it will have on the respective codon and to which amino acid it will be translated. 2. Based on the answer in (a), use the DNA sequence of bradykinin to describe the outcome of the replication step. 5. You have the picture of DNA transcription and mRNA translation between prokaryotic and eukaryotic cells.Instruction: Make a comparative chart showing the differences between the two cells. (image) 7. Methylations. Describe…
18) which of the following statements is correct? A proteins make MRNA which then makes genes B genes make proteins which then make mRNA C genes make mRNA which then make proteins d- MRNA is make proteins which then make genes E- MRNAs make genes which then make proteins
1. Using the genetic code, determine the sequence of amino acids encoded by the mRNA codocn sequence 5' GCC-AUG-GUA-AAA-UGC-GAC-CCC 3' 2. Using the genetic code, determine the sequence of amino acids encoded by the mRNA codocn sequence 5' CAU-CCU-CAC-ACU-GUU-UGU-UGG 3'
1. Identify the name of the correct amino acid that corresponds to the correct tRNA codon and mRNA codon. State the process used to convert to mRNA and tRNA.
1. What would be the amino acid sequence encoded by the mRNA5' C C A U G A C G U C G G A U C A A U G A G C 3' 2. If the nucleotide bolded and underlined in red in part 1 changes from C to a G, what type of mutation would that be? 3. What would happen to the amino acid sequence if the C bolded in red in part 1 is changed to a G? 4. What would happen to the amino acid sequence if the C bolded in red is deleted?
3. Briefly describe the function of the following in protein synthesis: a) rRNA, b) tRNA c) mRNA
1.Describe the journey of a protein, from its synthesis to its final destination 2. Explain the different stages of transcription and the role of the elements involved with the right terminology (template vs. non-transcribed strand, promoter, stop sequence, TATA box, general and specific transcription factors, RNA polymerase II, etc.); 3. Explain what the maturation (modifications) of pre-messenger RNA consists of and its role
1. Identify the major types of RNA in a cell and discuss their individual functions in relation to protein synthesis. 2. Compare the structural differences of sugars and bases in DNA and RNA molecules 3. What processing events differentiate eukaryotic mRNA from prokaryotic mRNA?
7. A segment of a DNA strand consists of ...GCTTAGACCTGA.... (a) Identify the expected nucleotide order in the complementary mRNA (b) Identify the sequence of amino acids coded for by this segment of DNA. (c) Describe the bond that forms during translation to link amino acids together. Identify the functional groups that react and the atoms involved.
1. Classify the type of mutation that have taken place: silent, missense and nonsense as a result of a single base substitution from UCG codon which codes for cysteine:a) AGC (ser): ________b) UGU (cys): ________c) GGC (gly): _______d) UGA (stop): _______e) UUC (phen): _______2. A single base addition and a single base deletion approximately 15 bases apart in the mRNA specifying the protein lysozyme from the bacterial virus T4 caused a change in the protein fromits wil-type composition….lys-ser-pro-ser-leu-asn-ala-ala-lys…..to the mutant form lys-val-his-his-leu-met-ala-alalys.a. Decipher the segment of mRNA for both the original protein and the double mutant.b. Which base was added? Which was deleted?3. Given is the 30 nucleotides in the human gene for hemoglobin (the oxygen-carrying protein in the red blood cells): 5’ TAC-CAC-GTG-GAC-TGA-GGA-CTC-CTC-TTC-AGA 3’a. What is the complementary strand?b. Deduce the mRNA in this coding region.c. What is the amino acid sequence based on this…
7. what are the types of processing a eukaryotic mRNA is subject to, and how do they occur?